MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2638 · 46 genes shown · anchor rsbW · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv2638 (requalified) — anti-sigma factor antagonist Rv2638 Rv1364c (family_assigned) — sigma factor regulatory protein Rv1364c rsbW (requalified) — anti-sigma B factor RsbW rsbW Rv3899c (family_assigned) — hypothetical protein Rv3899c Rv1354c (requalified) — bifunctional diguanylate cyclase/phosphodiesterase Rv1354c Rv2423 (requalified) — class I SAM-dependent methyltransferase Rv2423 fbiC (requalified) — bifunctional FO biosynthesis protein CofGH fbiC Rv3434c (family_assigned) — rhomboid-like protein Rv3434c Rv2079 (family_assigned) — alpha/beta hydrolase Rv2079 mkl (family_assigned) — ABC transporter ATP-binding protein mkl Rv1868 (family_assigned) — NAD(P)H-binding protein Rv1868 dedA (family_assigned) — DedA family protein dedA Rv2778c (family_assigned) — SRPBCC family protein Rv2778c rsfA (requalified) — anti-sigma-F factor antagonist RsfA rsfA rsfB (family_assigned) — STAS domain-containing protein rsfB Rv1904 (requalified) — anti-sigma factor antagonist Rv1904 sigF (requalified) — RNA polymerase sigma factor SigF sigF usfY (family_assigned) — hypothetical protein usfY eccD2 (family_assigned) — type VII secretion system ESX-2 subunit EccD2 eccD2 eccB2 (family_assigned) — type VII secretion system ESX-2 subunit EccB2 eccB2 eccC2 (family_assigned) — type VII secretion system ESX-2 FtsK/SpoIIIE famil eccC2 Rv3900c (family_assigned) — hypothetical protein Rv3900c PE_PGRS16 (family_assigned) — PE-PGRS family protein PE_PGRS16 PE_PGRS16 moeY (family_assigned) — Rv1355c family protein moeY Rv1353c (family_assigned) — TetR/AcrR family transcriptional regulator C-termi Rv1353c Rv1356c (requalified) — hypothetical protein Rv1356c Rv1358 (family_assigned) — LuxR C-terminal-related transcriptional regulator Rv1358 Rv1357c (requalified) — cyclic diguanylate phosphodiesterase Rv1357c cobIJ (requalified) — precorrin-2 C(20)-methyltransferase cobIJ Rv2067c (requalified) — class I SAM-dependent methyltransferase Rv2067c Rv3435c (family_assigned) — DUF4436 domain-containing protein Rv3435c Rv3166c (family_assigned) — DUF4129 domain-containing protein Rv3166c fbiA (requalified) — 2-phospho-L-lactate transferase fbiA thiG (requalified) — thiazole synthase thiG thiC (requalified) — phosphomethylpyrimidine synthase ThiC thiC thiE (requalified) — thiamine phosphate synthase thiE Rv3433c (requalified) — NAD(P)H-hydrate dehydratase Rv3433c gadB (requalified) — glutamate decarboxylase gadB glmS (requalified) — glutamine--fructose-6-phosphate transaminase (isom glmS Rv0180c (family_assigned) — YhgE/Pip domain-containing protein Rv0180c Rv2078 (family_assigned) — DUF2563 family protein Rv2078 lppJ (family_assigned) — hypothetical protein lppJ Rv1359 (family_assigned) — transcriptional regulator Rv1359 Rv0048c (family_assigned) — DUF1707 domain-containing protein Rv0048c yrbE1A (family_assigned) — ABC transporter permease yrbE1A yrbE1B (family_assigned) — ABC transporter permease yrbE1B

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.