MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2590 · 39 genes shown · anchor pks13 · open gene page → · ← back to 1 hop

Evidence: Min score 0
fadD9 (requalified) — carboxylic acid reductase fadD9 pks13 (requalified) — polyketide synthase Pks13 pks13 mbtB (requalified) — phenyloxazoline synthase MbtB mbtB pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 pks1 (requalified) — polyketide synthase pks1 mas (requalified) — mycocerosate synthase mas pks12 (requalified) — type I polyketide synthase pks12 pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC pks4 (requalified) — polyketide beta-ketoacyl synthase pks4 pks7 (requalified) — type I polyketide synthase pks7 ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB gmk (requalified) — guanylate kinase gmk mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH fas (requalified) — fatty acid synthase fas nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4 mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA mbtE (requalified) — peptide synthetase mbtE mbtC (requalified) — polyketide synthetase MbtC mbtC fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD papA1 (requalified) — acyltransferase PapA1 papA1 pks15 (requalified) — polyketide synthase pks15 ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD pks3 (requalified) — polyketide beta-ketoacyl synthase pks3 papA3 (requalified) — acyltransferase PapA3 papA3 pks8 (requalified) — polyketide synthase pks8 pks9 (requalified) — type I polyketide synthase pks9 pks17 (requalified) — polyketide synthase pks17 ppsA (requalified) — phthiocerol type I polyketide synthase PpsA ppsA fadD26 (requalified) — long-chain-fatty-acid--AMP ligase FAAL26/FadD26 fadD26 rpoZ (family_assigned) — DNA-directed RNA polymerase subunit omega rpoZ guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA apt (requalified) — adenine phosphoribosyltransferase apt pykA (requalified) — pyruvate kinase pykA ndkA (requalified) — nucleoside-diphosphate kinase ndkA hpt (requalified) — hypoxanthine phosphoribosyltransferase hpt

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.