MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2574 · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv2574 (family_assigned) — SRPBCC family protein Rv2574 Rv2573 (requalified) — 2-dehydropantoate 2-reductase Rv2573 Rv2575 (requalified) — neutral zinc metallopeptidase Rv2575 Rv1057 (family_assigned) — YncE family protein Rv1057 Rv0955 (family_assigned) — DUF6350 family protein Rv0955 Rv2633c (requalified) — non-heme di-iron catalase Rv2633c mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG Rv1132 (family_assigned) — DUF3556 domain-containing protein Rv1132 Rv1157c (dark) — hypothetical protein Rv1157c Rv3604c (dark) — DUF6779 domain-containing protein Rv3604c Rv3169 (family_assigned) — hypothetical protein Rv3169 Rv3577 (requalified) — hypothetical protein Rv3577 aftD (family_assigned) — DUF3367 domain-containing protein aftD panC (requalified) — pantoate--beta-alanine ligase panC panB (requalified) — 3-methyl-2-oxobutanoate hydroxymethyltransferase panB aspS (requalified) — aspartate--tRNA ligase aspS Rv1000c (family_assigned) — hypothetical protein Rv1000c Rv2510c (family_assigned) — DUF853 domain-containing protein Rv2510c Rv3092c (family_assigned) — DUF808 domain-containing protein Rv3092c Rv2571c (family_assigned) — aromatic acid exporter family protein Rv2571c fadD14 (requalified) — long-chain fatty acid--CoA ligase fadD14 PE_PGRS17 (family_assigned) — PE-PGRS family protein PE_PGRS17 PE_PGRS17 PE_PGRS18 (family_assigned) — PE-PGRS family protein PE_PGRS18 PE_PGRS18 mbtB (requalified) — phenyloxazoline synthase MbtB mbtB Rv1061 (requalified) — class II glutamine amidotransferase Rv1061 Rv1062 (family_assigned) — patatin-like phospholipase family protein Rv1062 Rv0954 (requalified) — DUF5336 domain-containing protein Rv0954 purN (requalified) — phosphoribosylglycinamide formyltransferase purN purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH pimE (requalified) — mannosyltransferase pimE Rv2632c (family_assigned) — DUF1876 domain-containing protein Rv2632c Rv3896c (requalified) — transglycosylase Rv3896c Rv1978 (requalified) — class I SAM-dependent methyltransferase Rv1978 Rv0688 (requalified) — FAD/NAD(P)-binding oxidoreductase Rv0688 Rv1869c (requalified) — FAD-dependent oxidoreductase Rv1869c mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtF (requalified) — peptide synthetase mbtF mbtE (requalified) — peptide synthetase mbtE mbtD (requalified) — mycobactin polyketide synthase MbtD mbtD mbtC (requalified) — polyketide synthetase MbtC mbtC prpC (requalified) — 2-methylcitrate synthase prpC prpD (requalified) — 2-methylcitrate dehydratase prpD Rv1129c (family_assigned) — short-chain fatty acyl-CoA regulator family protei Rv1129c Rv3830c (family_assigned) — TetR/AcrR family transcriptional regulator Rv3830c Rv1158c (dark) — hypothetical protein Rv1158c Rv2721c (family_assigned) — LGFP repeat-containing protein Rv2721c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.