MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2555c · 46 genes shown · anchor ruvX · open gene page → · ← back to 1 hop

Evidence: Min score 0
alaS (requalified) — alanine--tRNA ligase alaS ruvX (requalified) — Holliday junction resolvase RuvX ruvX mltG (requalified) — endolytic transglycosylase MltG mltG Rv1691 (family_assigned) — hypothetical protein Rv1691 Rv3529c (requalified) — TLR2-mediated response inhibitor Rv3529c Rv2267c (requalified) — sulfotransferase Rv2267c aroE (requalified) — shikimate dehydrogenase aroE pheT (family_assigned) — phenylalanine--tRNA ligase subunit beta pheT PE_PGRS62 (family_assigned) — PE-PGRS family protein PE_PGRS62 PE_PGRS62 PE23 (family_assigned) — PE family protein PE23 PE23 TB22.2 (family_assigned) — RsiV family protein TB22.2 PE_PGRS12 (family_assigned) — PE-PGRS family protein PE_PGRS12 PE_PGRS12 thrS (requalified) — threonine--tRNA ligase thrS Rv2551c (family_assigned) — A24 family peptidase Rv2551c Rv2556c (requalified) — secondary thiamine-phosphate synthase enzyme YjbQ Rv2556c Rv0038 (family_assigned) — YqgE/AlgH family protein Rv0038 eccE5 (family_assigned) — type VII secretion system ESX-5 subunit EccE5 eccE5 Rv1692 (family_assigned) — HAD-IIA family hydrolase Rv1692 htpG (requalified) — molecular chaperone HtpG htpG ppnK (requalified) — NAD kinase ppnK tlyA (requalified) — 16S/23S rRNA (cytidine-2'-O)-methyltransferase Tly tlyA Rv1693 (dark) — hypothetical protein Rv1693 Rv3530c (family_assigned) — SDR family oxidoreductase Rv3530c Rv3531c (family_assigned) — hypothetical protein Rv3531c rpoA (family_assigned) — DNA-directed RNA polymerase subunit alpha rpoA mftF (requalified) — mycofactocin biosynthesis glycosyltransferase MftF mftF cyp128 (requalified) — cytochrome P450 cyp128 rpoZ (family_assigned) — DNA-directed RNA polymerase subunit omega rpoZ aroA (requalified) — 3-phosphoshikimate 1-carboxyvinyltransferase aroA aroB (requalified) — 3-dehydroquinate synthase aroB aroK (requalified) — shikimate kinase AroK aroK aroD (requalified) — type II 3-dehydroquinate dehydratase aroD pheS (family_assigned) — phenylalanine--tRNA ligase subunit alpha pheS leuS (requalified) — leucine--tRNA ligase leuS ileS (requalified) — isoleucine--tRNA ligase ileS rpsB (requalified) — 30S ribosomal protein S2 rpsB rpoB (family_assigned) — DNA-directed RNA polymerase subunit beta rpoB rplO (requalified) — 50S ribosomal protein L15 rplO Rv2133c (family_assigned) — SCO1664 family protein Rv2133c helZ (requalified) — DEAD/DEAH box helicase helZ PE_PGRS13 (family_assigned) — PE-PGRS family protein PE_PGRS13 PE_PGRS13 infB (requalified) — translation initiation factor IF-2 infB rpsO (requalified) — 30S ribosomal protein S15 rpsO Rv2613c (requalified) — ATP adenylyltransferase Rv2613c rpmF (requalified) — 50S ribosomal protein L32 rpmF rplC (requalified) — 50S ribosomal protein L3 rplC

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.