Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2544 · 46 genes shown · anchor lppA · open gene page → · ← back to 1 hop

Evidence: Min score 0
lppB (family_assigned) — LppA family lipoprotein lppB lppA (family_assigned) — LppA family lipoprotein lppA vapB18 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB18 Rv2542 (family_assigned) — alpha/beta hydrolase family protein Rv2542 vapC18 (family_assigned) — PIN domain nuclease vapC18 vapC19 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC19 vapB19 (family_assigned) — CopG family transcriptional regulator vapB19 PPE59 (family_assigned) — PPE family protein PPE59 PPE59 tatB (requalified) — Sec-independent protein translocase protein TatB tatB gyrA (family_assigned) — DNA topoisomerase (ATP-hydrolyzing) subunit A gyrA cspA (requalified) — cold shock protein CspA cspA lldD2 (requalified) — quinone-dependent L-lactate dehydrogenase lldD2 PPE69 (family_assigned) — PPE family protein PPE69 PPE69 eccD1 (family_assigned) — type VII secretion system ESX-1 subunit EccD1 eccD1 eccE1 (family_assigned) — type VII secretion system ESX-1 subunit EccE1 eccE1 espK (family_assigned) — ESX-1 secretion-associated protein EspK espK eccB1 (family_assigned) — type VII secretion system ESX-1 subunit EccB1 eccB1 esxA (requalified) — ESAT-6 protein EsxA esxA eccCa1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCa1 vapC26 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC26 vapC25 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC25 vapC31 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC31 Rv3098A (family_assigned) — PemK-like protein Rv3098A vapB44 (family_assigned) — CopG family transcriptional regulator vapB44 PPE58 (family_assigned) — PPE family protein PPE58 PPE58 Rv2658c (family_assigned) — hypothetical protein Rv2658c PE_PGRS37 (family_assigned) — PE-PGRS family protein PE_PGRS37 PE_PGRS37 htrA (requalified) — serine protease HtrA htrA guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA tatC (family_assigned) — twin-arginine translocase subunit TatC tatC rseA (requalified) — anti-sigma E factor RseA rseA Rv1337 (family_assigned) — rhomboid family intramembrane serine protease Rv1337 sigE (requalified) — RNA polymerase sigma factor SigE sigE gyrB (family_assigned) — DNA topoisomerase (ATP-hydrolyzing) subunit B gyrB Rv0007 (dark) — DUF3566 domain-containing protein Rv0007 eccE5 (family_assigned) — type VII secretion system ESX-5 subunit EccE5 eccE5 ubiA (requalified) — decaprenyl-phosphate phosphoribosyltransferase ubiA atpH (family_assigned) — F0F1 ATP synthase subunit B/delta atpH rplK (requalified) — 50S ribosomal protein L11 rplK rpsL (requalified) — 30S ribosomal protein S12 rpsL rplO (requalified) — 50S ribosomal protein L15 rplO tuf (requalified) — elongation factor Tu tuf rpmJ (requalified) — 50S ribosomal protein L36 rpmJ esxJ (requalified) — type VII secretion system ESX-5 protein EsxJ esxJ rpmE (requalified) — 50S ribosomal protein L31 rpmE Rv1871c (family_assigned) — nitroreductase family deazaflavin-dependent oxidor Rv1871c

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.