MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2543 · 46 genes shown · anchor lppB · open gene page → · ← back to 1 hop

Evidence: Min score 0
lppA (family_assigned) — LppA family lipoprotein lppA lppB (family_assigned) — LppA family lipoprotein lppB vapB18 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB18 vapC18 (family_assigned) — PIN domain nuclease vapC18 Rv2542 (family_assigned) — alpha/beta hydrolase family protein Rv2542 vapC19 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC19 vapB19 (family_assigned) — CopG family transcriptional regulator vapB19 lldD2 (requalified) — quinone-dependent L-lactate dehydrogenase lldD2 cspA (requalified) — cold shock protein CspA cspA tatB (requalified) — Sec-independent protein translocase protein TatB tatB PPE59 (family_assigned) — PPE family protein PPE59 PPE59 opcA (requalified) — glucose-6-phosphate dehydrogenase assembly protein opcA PPE69 (family_assigned) — PPE family protein PPE69 PPE69 vapC26 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC26 eccD1 (family_assigned) — type VII secretion system ESX-1 subunit EccD1 eccD1 eccE1 (family_assigned) — type VII secretion system ESX-1 subunit EccE1 eccE1 espK (family_assigned) — ESX-1 secretion-associated protein EspK espK eccB1 (family_assigned) — type VII secretion system ESX-1 subunit EccB1 eccB1 esxA (requalified) — ESAT-6 protein EsxA esxA eccCa1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCa1 vapC25 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC25 vapC31 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC31 Rv3098A (family_assigned) — PemK-like protein Rv3098A vapB44 (family_assigned) — CopG family transcriptional regulator vapB44 Rv1871c (family_assigned) — nitroreductase family deazaflavin-dependent oxidor Rv1871c pykA (requalified) — pyruvate kinase pykA mftD (requalified) — pre-mycofactocin synthase MftD mftD pca (requalified) — pyruvate carboxylase pca Rv2455c (family_assigned) — 2-oxoacid:acceptor oxidoreductase subunit alpha Rv2455c mez (requalified) — NAD-dependent malic enzyme mez rpsL (requalified) — 30S ribosomal protein S12 rpsL rplO (requalified) — 50S ribosomal protein L15 rplO tuf (requalified) — elongation factor Tu tuf rpmJ (requalified) — 50S ribosomal protein L36 rpmJ esxJ (requalified) — type VII secretion system ESX-5 protein EsxJ esxJ rpmE (requalified) — 50S ribosomal protein L31 rpmE htrA (requalified) — serine protease HtrA htrA guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA tatC (family_assigned) — twin-arginine translocase subunit TatC tatC rseA (requalified) — anti-sigma E factor RseA rseA Rv1337 (family_assigned) — rhomboid family intramembrane serine protease Rv1337 sigE (requalified) — RNA polymerase sigma factor SigE sigE PPE58 (family_assigned) — PPE family protein PPE58 PPE58 Rv2658c (family_assigned) — hypothetical protein Rv2658c PE_PGRS37 (family_assigned) — PE-PGRS family protein PE_PGRS37 PE_PGRS37 devB (requalified) — 6-phosphogluconolactonase devB

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.