MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2524c · 37 genes shown · anchor pks7 · open gene page → · ← back to 1 hop

Evidence: Min score 0
fas (requalified) — fatty acid synthase fas pks7 (requalified) — type I polyketide synthase pks7 pks17 (requalified) — polyketide synthase pks17 pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 mas (requalified) — mycocerosate synthase mas accD3 (family_assigned) — carboxyl transferase domain-containing protein accD3 pks6 (requalified) — membrane bound polyketide synthase pks6 ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB pks4 (requalified) — polyketide beta-ketoacyl synthase pks4 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC ppsA (requalified) — phthiocerol type I polyketide synthase PpsA ppsA pks1 (requalified) — polyketide synthase pks1 pks13 (requalified) — polyketide synthase Pks13 pks13 mbtB (requalified) — phenyloxazoline synthase MbtB mbtB pks8 (requalified) — polyketide synthase pks8 pks9 (requalified) — type I polyketide synthase pks9 fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD pks15 (requalified) — polyketide synthase pks15 mbtC (requalified) — polyketide synthetase MbtC mbtC pks3 (requalified) — polyketide beta-ketoacyl synthase pks3 pks12 (requalified) — type I polyketide synthase pks12 papA1 (requalified) — acyltransferase PapA1 papA1 accA1 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA1 accA3 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA3 accA2 (family_assigned) — biotin carboxylase N-terminal domain-containing pr accA2 Rv1722 (requalified) — biotin carboxylase Rv1722 fabH (requalified) — beta-ketoacyl-ACP synthase III fabH fadD30 (requalified) — long-chain-fatty-acid--AMP ligase FadD30 fadD30 nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp mbtE (requalified) — peptide synthetase mbtE fadD26 (requalified) — long-chain-fatty-acid--AMP ligase FAAL26/FadD26 fadD26 ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD papA3 (requalified) — acyltransferase PapA3 papA3 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.