MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2495c · 39 genes shown · anchor bkdB · open gene page → · ← back to 1 hop

Evidence: Min score 0
bkdC (family_assigned) — dihydrolipoamide acetyltransferase family protein bkdC bkdB (family_assigned) — 3-methyl-2-oxobutanoate dehydrogenase subunit beta bkdB bkdA (family_assigned) — pyruvate dehydrogenase (acetyl-transferring) E1 co bkdA lpdC (requalified) — dihydrolipoyl dehydrogenase lpdC aceE (requalified) — pyruvate dehydrogenase E1 component aceE Rv0843 (family_assigned) — thiamine pyrophosphate-dependent dehydrogenase E1 Rv0843 accA1 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA1 Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c gltA2 (requalified) — citrate synthase gltA2 citA (requalified) — citrate synthase 2 citA prpC (requalified) — 2-methylcitrate synthase prpC lpdA (requalified) — NAD(P)H-quinone dehydrogenase lpdA sucC (family_assigned) — ADP-forming succinate--CoA ligase subunit beta sucC dlaT (requalified) — 2-oxoglutarate dehydrogenase%2C E2 component%2C di dlaT mez (requalified) — NAD-dependent malic enzyme mez gcvH (requalified) — glycine cleavage system protein GcvH gcvH pykA (requalified) — pyruvate kinase pykA Rv1734c (family_assigned) — hypothetical protein Rv1734c Rv0842 (requalified) — MFS transporter Rv0842 accD1 (family_assigned) — acetyl-/propionyl-CoA carboxylase subunit beta accD1 accD3 (family_assigned) — carboxyl transferase domain-containing protein accD3 accD5 (family_assigned) — acyl-CoA carboxylase subunit beta accD5 accD6 (family_assigned) — acyl-CoA carboxylase subunit beta accD6 fas (requalified) — fatty acid synthase fas citE (family_assigned) — citrate (pro-3S)-lyase subunit beta citE Rv0794c (requalified) — oxidoreductase Rv0794c garA (requalified) — glycogen accumulation regulator GarA garA sthA (requalified) — Si-specific NAD(P)(+) transhydrogenase sthA mtr (requalified) — mycothione reductase mtr acn (requalified) — iron-regulated aconitate hydratase Acn acn mdh (requalified) — malate dehydrogenase mdh acs (requalified) — acetate--CoA ligase acs glcB (requalified) — malate synthase G glcB prpD (requalified) — 2-methylcitrate dehydratase prpD glpD2 (requalified) — glycerol-3-phosphate dehydrogenase/oxidase glpD2 sucD (family_assigned) — succinyl-CoA ligase subunit alpha sucD sdhC (family_assigned) — succinate dehydrogenase%2C cytochrome b556 subunit sdhC sdhB (family_assigned) — succinate dehydrogenase iron-sulfur subunit sdhB sdhD (family_assigned) — succinate dehydrogenase hydrophobic membrane ancho sdhD

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.