Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2451 · 26 genes shown · anchor rpfE · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv2451 (dark) — hypothetical protein Rv2451 rpfE (requalified) — resuscitation-promoting factor protein RpfE rpfE Rv2449c (family_assigned) — trans-acting enoyl reductase family protein Rv2449c Rv2867c (family_assigned) — GNAT family N-acetyltransferase Rv2867c relG (family_assigned) — type II toxin-antitoxin system RelE/ParE family to relG Rv1954A (dark) — Hypothetical protein Rv1954A Rv0007 (dark) — DUF3566 domain-containing protein Rv0007 Rv3268 (family_assigned) — hypothetical protein Rv3268 Rv2286c (family_assigned) — DsbA family protein Rv2286c valS (requalified) — valine--tRNA ligase valS folC (requalified) — bifunctional tetrahydrofolate synthase/dihydrofola folC Rv2446c (dark) — DUF4233 domain-containing protein Rv2446c ndkA (requalified) — nucleoside-diphosphate kinase ndkA htdX (requalified) — 3-hydroxyacyl-thioester dehydratase HtdX htdX gcpE (requalified) — flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-e gcpE rip (requalified) — zinc metalloprotease Rip rip dxr (requalified) — 1-deoxy-D-xylulose-5-phosphate reductoisomerase dxr mpa (requalified) — proteasome ATPase mpa Rv1488 (family_assigned) — SPFH domain-containing protein Rv1488 Rv2239c (family_assigned) — hypothetical protein Rv2239c relF (requalified) — type II toxin-antitoxin system antitoxin RelF relF relB (family_assigned) — type II toxin-antitoxin system Phd/YefM family ant relB mazF2 (family_assigned) — type II toxin-antitoxin system PemK/MazF family to mazF2 mazF5 (family_assigned) — type II toxin-antitoxin system PemK/MazF family to mazF5 Rv2864c (family_assigned) — penicillin-binding protein Rv2864c relJ (requalified) — type II toxin-antitoxin system antitoxin RelJ relJ

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.