MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2449c · 46 genes shown · anchor rpfE · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv2449c (family_assigned) — trans-acting enoyl reductase family protein Rv2449c rpfE (requalified) — resuscitation-promoting factor protein RpfE rpfE valS (requalified) — valine--tRNA ligase valS folC (requalified) — bifunctional tetrahydrofolate synthase/dihydrofola folC Rv2446c (dark) — DUF4233 domain-containing protein Rv2446c ndkA (requalified) — nucleoside-diphosphate kinase ndkA htdX (requalified) — 3-hydroxyacyl-thioester dehydratase HtdX htdX Rv2451 (dark) — hypothetical protein Rv2451 inhA (requalified) — NADH-dependent enoyl-ACP reductase InhA inhA Rv1544 (family_assigned) — SDR family oxidoreductase Rv1544 tesA (requalified) — thioesterase TesA tesA mbtC (requalified) — polyketide synthetase MbtC mbtC Rv1954A (dark) — Hypothetical protein Rv1954A Rv0007 (dark) — DUF3566 domain-containing protein Rv0007 Rv3268 (family_assigned) — hypothetical protein Rv3268 Rv2286c (family_assigned) — DsbA family protein Rv2286c ileS (requalified) — isoleucine--tRNA ligase ileS leuS (requalified) — leucine--tRNA ligase leuS guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA folP1 (requalified) — dihydropteroate synthase folP1 folP2 (requalified) — dihydropteroate synthase folP2 dfrA (requalified) — dihydrofolate reductase dfrA thyA (requalified) — thymidylate synthase ThyA thyA Rv0556 (family_assigned) — DUF3592 domain-containing protein Rv0556 Rv2732c (family_assigned) — hypothetical protein Rv2732c Rv3205c (family_assigned) — hypothetical protein Rv3205c Rv0863 (family_assigned) — hypothetical protein Rv0863 rpsJ (requalified) — 30S ribosomal protein S10 rpsJ rpsL (requalified) — 30S ribosomal protein S12 rpsL rpsO (requalified) — 30S ribosomal protein S15 rpsO rpsB (requalified) — 30S ribosomal protein S2 rpsB rpsG (requalified) — 30S ribosomal protein S7 rpsG rpsP (requalified) — 30S ribosomal protein S16 rpsP fabG4 (requalified) — 3-oxoacyl-ACP reductase fabG4 fadA2 (requalified) — acetyl-CoA C-acetyltransferase fadA2 fadB (requalified) — fatty oxidation protein FadB fadB fadE23 (family_assigned) — acyl-CoA dehydrogenase family protein fadE23 fadE24 (family_assigned) — acyl-CoA dehydrogenase family protein fadE24 fadE8 (family_assigned) — acyl-CoA dehydrogenase family protein fadE8 Rv2867c (family_assigned) — GNAT family N-acetyltransferase Rv2867c relG (family_assigned) — type II toxin-antitoxin system RelE/ParE family to relG fas (requalified) — fatty acid synthase fas fabG1 (requalified) — 3-oxoacyl-ACP reductase FabG1 fabG1 accD3 (family_assigned) — carboxyl transferase domain-containing protein accD3 hemZ (requalified) — ferrochelatase hemZ fabH (requalified) — beta-ketoacyl-ACP synthase III fabH

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.