MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2447c · 46 genes shown · anchor folP1 · open gene page → · ← back to 1 hop

Evidence: Min score 0
folC (requalified) — bifunctional tetrahydrofolate synthase/dihydrofola folC folP1 (requalified) — dihydropteroate synthase folP1 folP2 (requalified) — dihydropteroate synthase folP2 valS (requalified) — valine--tRNA ligase valS Rv2446c (dark) — DUF4233 domain-containing protein Rv2446c dfrA (requalified) — dihydrofolate reductase dfrA thyA (requalified) — thymidylate synthase ThyA thyA ndkA (requalified) — nucleoside-diphosphate kinase ndkA glyA1 (requalified) — serine hydroxymethyltransferase glyA1 glyA2 (requalified) — serine hydroxymethyltransferase glyA2 Rv2449c (family_assigned) — trans-acting enoyl reductase family protein Rv2449c folB (requalified) — dihydroneopterin aldolase folB folE (requalified) — GTP cyclohydrolase I FolE folE folK (requalified) — 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine folK ftsH (requalified) — ATP-dependent zinc metalloprotease FtsH ftsH Rv0812 (requalified) — 4-amino-4-deoxychorismate lyase Rv0812 gpgS (requalified) — glucosyl-3-phosphoglycerate synthase gpgS ileS (requalified) — isoleucine--tRNA ligase ileS leuS (requalified) — leucine--tRNA ligase leuS guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA Rv0556 (family_assigned) — DUF3592 domain-containing protein Rv0556 Rv2732c (family_assigned) — hypothetical protein Rv2732c Rv3205c (family_assigned) — hypothetical protein Rv3205c Rv0863 (family_assigned) — hypothetical protein Rv0863 thyX (requalified) — FAD-dependent thymidylate synthase thyX fmt (requalified) — methionyl-tRNA formyltransferase fmt purN (requalified) — phosphoribosylglycinamide formyltransferase purN dut (requalified) — deoxyuridine 5'-triphosphate nucleotidohydrolase dut folD (requalified) — bifunctional methylenetetrahydrofolate dehydrogena folD tmk (requalified) — dTMP kinase tmk rpsJ (requalified) — 30S ribosomal protein S10 rpsJ rpsL (requalified) — 30S ribosomal protein S12 rpsL rpsO (requalified) — 30S ribosomal protein S15 rpsO rpsB (requalified) — 30S ribosomal protein S2 rpsB rpsG (requalified) — 30S ribosomal protein S7 rpsG rpsP (requalified) — 30S ribosomal protein S16 rpsP gcvB (requalified) — aminomethyl-transferring glycine dehydrogenase gcvB gcvT (requalified) — aminomethyltransferase gcvT purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH gcvH (requalified) — glycine cleavage system protein GcvH gcvH sdaA (requalified) — L-serine ammonia-lyase sdaA rpfE (requalified) — resuscitation-promoting factor protein RpfE rpfE htdX (requalified) — 3-hydroxyacyl-thioester dehydratase HtdX htdX Rv3605c (family_assigned) — DUF3180 domain-containing protein Rv3605c ribA2 (requalified) — bifunctional 3%2C4-dihydroxy-2-butanone-4-phosphat ribA2 ribA1 (requalified) — riboflavin biosynthesis protein RibA ribA1

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.