MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2438c · 43 genes shown · anchor nadR · open gene page → · ← back to 1 hop

Evidence: Min score 0
nadE (requalified) — NAD(+) synthase nadE nadR (requalified) — nicotinamide-nucleotide adenylyltransferase nadR nadD (requalified) — nicotinate-nucleotide adenylyltransferase nadD cobB (requalified) — NAD-dependent protein deacylase cobB ppnK (requalified) — NAD kinase ppnK sthA (requalified) — Si-specific NAD(P)(+) transhydrogenase sthA nudC (requalified) — NAD(+) diphosphatase nudC pntB (family_assigned) — NAD(P)(+) transhydrogenase (Re/Si-specific) subuni pntB pntAb (family_assigned) — NAD(P) transhydrogenase subunit alpha pntAb pntAa (family_assigned) — Re/Si-specific NAD(P)(+) transhydrogenase subunit pntAa guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA icd1 (requalified) — NADP-dependent isocitrate dehydrogenase icd1 Rv3728 (requalified) — MFS transporter Rv3728 pncB2 (requalified) — nicotinate phosphoribosyltransferase pncB2 pncB1 (requalified) — nicotinate phosphoribosyltransferase pncB1 cinA (requalified) — competence/damage-inducible protein A cinA rsfS (requalified) — ribosome silencing factor rsfS gpgP (requalified) — glucosyl-3-phosphoglycerate phosphatase gpgP Rv1152 (family_assigned) — GntR family transcriptional regulator Rv1152 pncA (requalified) — pyrazinamidase PncA pncA tlyA (requalified) — 16S/23S rRNA (cytidine-2'-O)-methyltransferase Tly tlyA Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c bkdB (family_assigned) — 3-methyl-2-oxobutanoate dehydrogenase subunit beta bkdB dlaT (requalified) — 2-oxoglutarate dehydrogenase%2C E2 component%2C di dlaT nadC (requalified) — carboxylating nicotinate-nucleotide diphosphorylas nadC ald (requalified) — alanine dehydrogenase ald guaB2 (requalified) — IMP dehydrogenase guaB2 guaB1 (family_assigned) — GuaB1 family IMP dehydrogenase-related protein guaB1 guaB3 (family_assigned) — GuaB3 family IMP dehydrogenase-related protein guaB3 apt (requalified) — adenine phosphoribosyltransferase apt argS (requalified) — arginine--tRNA ligase argS rplK (requalified) — 50S ribosomal protein L11 rplK acn (requalified) — iron-regulated aconitate hydratase Acn acn icd2 (requalified) — NADP-dependent isocitrate dehydrogenase icd2 Rv2455c (family_assigned) — 2-oxoacid:acceptor oxidoreductase subunit alpha Rv2455c Rv2454c (family_assigned) — 2-oxoacid:ferredoxin oxidoreductase subunit beta Rv2454c mdh (requalified) — malate dehydrogenase mdh Rv1714 (family_assigned) — SDR family oxidoreductase Rv1714 fadB3 (requalified) — 3-hydroxybutyryl-CoA dehydrogenase FadB fadB3 Rv1716 (family_assigned) — hypothetical protein Rv1716 Rv1718 (requalified) — 3-keto-5-aminohexanoate cleavage protein Rv1718 Rv1358 (family_assigned) — LuxR C-terminal-related transcriptional regulator Rv1358 Rv3727 (requalified) — FAD-dependent oxidoreductase Rv3727

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.