MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2425c · 45 genes shown · anchor proA · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv2425c (family_assigned) — VWA domain-containing protein Rv2425c Rv2426c (family_assigned) — MoxR family ATPase Rv2426c proA (requalified) — glutamate-5-semialdehyde dehydrogenase proA Rv0370c (family_assigned) — MoxR family ATPase Rv0370c Rv2417c (family_assigned) — DegV family protein Rv2417c mftF (requalified) — mycofactocin biosynthesis glycosyltransferase MftF mftF Rv2424c (requalified) — transposase Rv2424c mftC (requalified) — mycofactocin radical SAM maturase mftC octT (requalified) — diglucosylglycerate octanoyltransferase octT rsfS (requalified) — ribosome silencing factor rsfS nadD (requalified) — nicotinate-nucleotide adenylyltransferase nadD Rv0368c (family_assigned) — VWA domain-containing protein Rv0368c mftB (requalified) — mycofactocin biosynthesis chaperone MftB mftB Rv0373c (family_assigned) — aerobic carbon-monoxide dehydrogenase large subuni Rv0373c proB (requalified) — glutamate 5-kinase proB rocA (requalified) — L-glutamate gamma-semialdehyde dehydrogenase rocA purQ (family_assigned) — phosphoribosylformylglycinamidine synthase subunit purQ atpA (family_assigned) — F0F1 ATP synthase subunit alpha atpA gadB (requalified) — glutamate decarboxylase gadB Rv0375c (family_assigned) — carbon monoxyde dehydrogenase medium subunit Rv0375c Rv0372c (family_assigned) — XdhC family protein Rv0372c Rv0371c (family_assigned) — NTP transferase domain-containing protein Rv0371c Rv0369c (requalified) — membrane oxidoreductase Rv0369c Rv2974c (family_assigned) — hypothetical protein Rv2974c gpgP (requalified) — glucosyl-3-phosphoglycerate phosphatase gpgP Rv2975c (family_assigned) — hypothetical protein Rv2975c mftE (requalified) — mycofactocin biosynthesis peptidyl-dipeptidase Mft mftE mftG (family_assigned) — mycofactocin system GMC family oxidoreductase MftG mftG mftD (requalified) — pre-mycofactocin synthase MftD mftD mftR (family_assigned) — mycofactocin system transcriptional regulator mftR Rv2177c (requalified) — transposase Rv2177c Rv0071 (family_assigned) — reverse transcriptase domain-containing protein Rv0071 Rv0691A (requalified) — mycofactocin precursor Rv0691A Rv2186c (requalified) — polyketide cyclase / dehydrase and lipid transport Rv2186c Rv2695 (requalified) — alpha/beta fold hydrolase Rv2695 rplN (requalified) — 50S ribosomal protein L14 rplN rplU (requalified) — 50S ribosomal protein L21 rplU rplS (requalified) — 50S ribosomal protein L19 rplS rplQ (requalified) — 50S ribosomal protein L17 rplQ rpmA (requalified) — 50S ribosomal protein L27 rpmA cinA (requalified) — competence/damage-inducible protein A cinA nadE (requalified) — NAD(+) synthase nadE ppnK (requalified) — NAD kinase ppnK cobB (requalified) — NAD-dependent protein deacylase cobB Rv0374c (family_assigned) — (2Fe-2S)-binding protein Rv0374c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.