Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2423 · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv2423 (requalified) — class I SAM-dependent methyltransferase Rv2423 cobIJ (requalified) — precorrin-2 C(20)-methyltransferase cobIJ Rv2067c (requalified) — class I SAM-dependent methyltransferase Rv2067c Rv3899c (family_assigned) — hypothetical protein Rv3899c Rv3435c (family_assigned) — DUF4436 domain-containing protein Rv3435c Rv3166c (family_assigned) — DUF4129 domain-containing protein Rv3166c Rv2079 (family_assigned) — alpha/beta hydrolase Rv2079 Rv0048c (family_assigned) — DUF1707 domain-containing protein Rv0048c eccD2 (family_assigned) — type VII secretion system ESX-2 subunit EccD2 eccD2 PE_PGRS16 (family_assigned) — PE-PGRS family protein PE_PGRS16 PE_PGRS16 Rv3843c (family_assigned) — DUF4328 domain-containing protein Rv3843c papA5 (requalified) — phthiocerol/phthiodiolone dimycocerosyl transferas papA5 Rv1359 (family_assigned) — transcriptional regulator Rv1359 cobM (requalified) — precorrin-4 C(11)-methyltransferase cobM cobH (requalified) — precorrin-8X methylmutase cobH cobK (requalified) — cobalt-precorrin-6A reductase cobK cobL (requalified) — bifunctional cobalt-precorrin-7 (C(5))-methyltrans cobL cobQ1 (requalified) — cobyric acid synthase cobQ1 cobG (requalified) — precorrin-3B synthase cobG blaC (requalified) — beta-lactamase blaC eccB2 (family_assigned) — type VII secretion system ESX-2 subunit EccB2 eccB2 eccC2 (family_assigned) — type VII secretion system ESX-2 FtsK/SpoIIIE famil eccC2 Rv3900c (family_assigned) — hypothetical protein Rv3900c Rv3434c (family_assigned) — rhomboid-like protein Rv3434c Rv3433c (requalified) — NAD(P)H-hydrate dehydratase Rv3433c Rv3163c (dark) — DUF58 domain-containing protein Rv3163c Rv3165c (dark) — hypothetical protein Rv3165c moxR3 (family_assigned) — MoxR family ATPase moxR3 Rv3162c (family_assigned) — integral membrane protein Rv3162c Rv2078 (family_assigned) — DUF2563 family protein Rv2078 lppJ (family_assigned) — hypothetical protein lppJ Rv1904 (requalified) — anti-sigma factor antagonist Rv1904 Rv3779 (family_assigned) — DUF6541 family protein Rv3779 Rv1171 (family_assigned) — hypothetical protein Rv1171 Rv0875c (dark) — DUF2771 domain-containing protein Rv0875c Rv0188 (requalified) — SPW repeat protein Rv0188 Rv3773c (family_assigned) — TIGR03086 family metal-binding protein Rv3773c mycP2 (requalified) — type VII secretion system ESX-2 serine protease my mycP2 Rv3888c (family_assigned) — MinD/ParA family protein Rv3888c eccA2 (family_assigned) — type VII secretion system ESX-2 AAA family ATPase eccA2 eccE2 (family_assigned) — type VII secretion system ESX-2 subunit EccE2 eccE2 Rv2082 (dark) — DUF5631 domain-containing protein Rv2082 PPE34 (family_assigned) — PPE family protein PPE34 PPE34 PPE54 (family_assigned) — PPE family protein PPE54 PPE54 PPE8 (family_assigned) — PPE family protein PPE8 PPE8 PPE56 (family_assigned) — PPE family protein PPE56 PPE56

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.