MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2393 · 46 genes shown · anchor cysH · open gene page → · ← back to 1 hop

Evidence: Min score 0
che1 (requalified) — ferrochelatase che1 cysH (requalified) — phosphoadenylyl-sulfate reductase cysH sirA (requalified) — sulfite reductase sirA ggtB (family_assigned) — gamma-glutamyltransferase family protein ggtB cysG (requalified) — uroporphyrinogen-III C-methyltransferase cysG hemY (requalified) — protoporphyrinogen oxidase hemY cysC (requalified) — adenylyl-sulfate kinase cysC hemD (requalified) — uroporphyrin-III C-methyltransferase hemD narH (family_assigned) — nitrate reductase subunit beta narH Rv2395 (family_assigned) — oligopeptide transporter%2C OPT family Rv2395 Rv2633c (requalified) — non-heme di-iron catalase Rv2633c narJ (family_assigned) — nitrate reductase subunit delta narJ narI (family_assigned) — respiratory nitrate reductase subunit gamma narI cysQ (requalified) — 3'(2')%2C5'-bisphosphate nucleotidase CysQ cysQ cysA2 (requalified) — sulfurtransferase cysA2 cysK1 (requalified) — O-acetylserine sulfhydrylase cysK1 Rv3684 (requalified) — lyase Rv3684 metB (requalified) — cystathionine gamma-synthase metB ggtA (requalified) — bifunctional cephalosporin acylase/gamma-glutamylt ggtA oplA (family_assigned) — hydantoinase B/oxoprolinase family protein oplA Rv0433 (requalified) — glutamate--cysteine ligase Rv0433 hemC (requalified) — hydroxymethylbilane synthase hemC Rv0260c (requalified) — uroporphyrinogen-III synthase Rv0260c cobIJ (requalified) — precorrin-2 C(20)-methyltransferase cobIJ Rv0259c (family_assigned) — sirohydrochlorin chelatase Rv0259c hemE (requalified) — uroporphyrinogen decarboxylase hemE hemZ (requalified) — ferrochelatase hemZ Rv2850c (family_assigned) — magnesium chelatase subunit D family protein Rv2850c hemQ (requalified) — hydrogen peroxide-dependent heme synthase hemQ Rv0958 (family_assigned) — ATP-binding protein Rv0958 echA15 (family_assigned) — enoyl-CoA hydratase/isomerase family protein echA15 subI (family_assigned) — sulfate ABC transporter substrate-binding protein subI cysD (family_assigned) — sulfate adenylyltransferase subunit CysD cysD cysT (family_assigned) — sulfate ABC transporter permease subunit CysT cysT cysW (family_assigned) — sulfate ABC transporter permease subunit CysW cysW cysA1 (family_assigned) — sulfate ABC transporter ATP-binding protein CysA cysA1 hemB (requalified) — porphobilinogen synthase hemB hemA (requalified) — glutamyl-tRNA reductase hemA Rv0514 (dark) — hypothetical protein Rv0514 narG (family_assigned) — nitrate reductase subunit alpha narG narX (family_assigned) — respiratory nitrate reductase subunit gamma narX narK2 (requalified) — nitrate transporter NarK narK2 narK1 (requalified) — nitrate/nitrite transporter narK1 aprA (requalified) — acid and phagosome regulated protein AprA aprA atpB (family_assigned) — F0F1 ATP synthase subunit A atpB Rv2632c (family_assigned) — DUF1876 domain-containing protein Rv2632c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.