MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2390c · 46 genes shown · anchor rpfD · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv2390c (family_assigned) — hypothetical protein Rv2390c rpfD (requalified) — resuscitation-promoting factor protein RpfD rpfD Rv3492c (requalified) — Mce associated protein Rv3492c pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 pks12 (requalified) — type I polyketide synthase pks12 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC mas (requalified) — mycocerosate synthase mas Rv1691 (family_assigned) — hypothetical protein Rv1691 Rv2267c (requalified) — sulfotransferase Rv2267c Rv3529c (requalified) — TLR2-mediated response inhibitor Rv3529c pks17 (requalified) — polyketide synthase pks17 mec (requalified) — CysO-cysteine peptidase mec Rv1954A (dark) — Hypothetical protein Rv1954A hemN (requalified) — oxygen-independent coproporphyrinogen III oxidase hemN Rv0007 (dark) — DUF3566 domain-containing protein Rv0007 Rv2466c (family_assigned) — Rv2466c family mycothiol-dependent reductase Rv2466c Rv2286c (family_assigned) — DsbA family protein Rv2286c mce4D (family_assigned) — virulence factor Mce family protein mce4D lprN (family_assigned) — Mce family lipoprotein LprN lprN mce4F (family_assigned) — virulence factor Mce family protein mce4F Rv3493c (requalified) — mammalian cell entry protein Rv3493c mce4A (family_assigned) — Mce family protein Mce4A mce4A mce4C (family_assigned) — virulence factor Mce family protein mce4C fas (requalified) — fatty acid synthase fas fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD mbtB (requalified) — phenyloxazoline synthase MbtB mbtB papA1 (requalified) — acyltransferase PapA1 papA1 ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB Rv1692 (family_assigned) — HAD-IIA family hydrolase Rv1692 htpG (requalified) — molecular chaperone HtpG htpG alaS (requalified) — alanine--tRNA ligase alaS ppnK (requalified) — NAD kinase ppnK tlyA (requalified) — 16S/23S rRNA (cytidine-2'-O)-methyltransferase Tly tlyA Rv1693 (dark) — hypothetical protein Rv1693 cyp128 (requalified) — cytochrome P450 cyp128 rpoA (family_assigned) — DNA-directed RNA polymerase subunit alpha rpoA mftF (requalified) — mycofactocin biosynthesis glycosyltransferase MftF mftF rpoZ (family_assigned) — DNA-directed RNA polymerase subunit omega rpoZ Rv3530c (family_assigned) — SDR family oxidoreductase Rv3530c Rv3531c (family_assigned) — hypothetical protein Rv3531c pks8 (requalified) — polyketide synthase pks8 pks9 (requalified) — type I polyketide synthase pks9 pks15 (requalified) — polyketide synthase pks15

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.