MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2389c · 46 genes shown · anchor hemN · open gene page → · ← back to 1 hop

Evidence: Min score 0
rpfD (requalified) — resuscitation-promoting factor protein RpfD rpfD Rv2390c (family_assigned) — hypothetical protein Rv2390c Rv1954A (dark) — Hypothetical protein Rv1954A hemN (requalified) — oxygen-independent coproporphyrinogen III oxidase hemN Rv0007 (dark) — DUF3566 domain-containing protein Rv0007 Rv2466c (family_assigned) — Rv2466c family mycothiol-dependent reductase Rv2466c Rv2286c (family_assigned) — DsbA family protein Rv2286c Rv3268 (family_assigned) — hypothetical protein Rv3268 Rv2771c (family_assigned) — flavodoxin family protein Rv2771c mshD (requalified) — mycothiol synthase mshD Rv0925c (family_assigned) — flavodoxin family protein Rv0925c otsB1 (requalified) — trehalose-6-phosphate phosphatase OtsB otsB1 otsB2 (requalified) — trehalose-phosphatase otsB2 Rv3492c (requalified) — Mce associated protein Rv3492c pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 pks12 (requalified) — type I polyketide synthase pks12 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC rpfE (requalified) — resuscitation-promoting factor protein RpfE rpfE rpfC (requalified) — resuscitation-promoting factor RpfC rpfC rpfA (requalified) — resuscitation-promoting factor protein RpfA rpfA Rv1861 (family_assigned) — GlsB/YeaQ/YmgE family stress response membrane pro Rv1861 higB (requalified) — type II toxin-antitoxin system toxin HigB higB Rv2879c (family_assigned) — Conserved hypothetical protein Rv2879c hemE (requalified) — uroporphyrinogen decarboxylase hemE gltB (family_assigned) — glutamate synthase large subunit gltB Rv2880c (family_assigned) — Conserved hypothetical protein Rv2880c gyrA (family_assigned) — DNA topoisomerase (ATP-hydrolyzing) subunit A gyrA Rv1024 (family_assigned) — septum formation initiator family protein Rv1024 gyrB (family_assigned) — DNA topoisomerase (ATP-hydrolyzing) subunit B gyrB Rv3909 (dark) — hypothetical protein Rv3909 Rv2164c (family_assigned) — hypothetical protein Rv2164c ptrp (family_assigned) — hypothetical protein ptrp rpiB (requalified) — ribose-5-phosphate isomerase B rpiB Rv3463 (requalified) — LLM class F420-dependent oxidoreductase Rv3463 Rv2464c (family_assigned) — Fpg/Nei family DNA glycosylase Rv2464c mca (requalified) — mycothiol conjugate amidase Mca mca mshB (requalified) — N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D- mshB yjcE (requalified) — Na(+)/H(+) transporter yjcE Rv3075c (requalified) — CoA ester lyase Rv3075c cdh (requalified) — CDP-diacylglycerol diphosphatase cdh Rv2288 (dark) — hypothetical protein Rv2288 lcp1 (requalified) — phosphotransferase Lcp1 lcp1 Rv1312 (family_assigned) — DUF2550 domain-containing protein Rv1312 rplF (requalified) — 50S ribosomal protein L6 rplF mas (requalified) — mycocerosate synthase mas

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.