MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2386c · 35 genes shown · anchor trpG · open gene page → · ← back to 1 hop

Evidence: Min score 0
mbtI (requalified) — salicylate synthase mbtI trpG (requalified) — anthranilate synthase component II trpG trpD (requalified) — anthranilate phosphoribosyltransferase trpD mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA trpC (requalified) — indole-3-glycerol phosphate synthase TrpC trpC mbtB (requalified) — phenyloxazoline synthase MbtB mbtB entC (requalified) — isochorismate synthase entC trpB (family_assigned) — tryptophan synthase subunit beta trpB trpA (family_assigned) — tryptophan synthase subunit alpha trpA aroF (requalified) — chorismate synthase aroF aroE (requalified) — shikimate dehydrogenase aroE trpE (requalified) — anthranilate synthase component I trpE Rv3402c (family_assigned) — DegT/DnrJ/EryC1/StrS family aminotransferase Rv3402c Rv1005c (requalified) — para-aminobenzoate synthase component I Rv1005c pks13 (requalified) — polyketide synthase Pks13 pks13 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtJ (requalified) — acetyl hydrolase mbtJ mbtE (requalified) — peptide synthetase mbtE mbtC (requalified) — polyketide synthetase MbtC mbtC pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 menD (requalified) — 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1 menD Rv2949c (family_assigned) — chorismate pyruvate-lyase family protein Rv2949c lgt (requalified) — prolipoprotein diacylglyceryl transferase lgt aroB (requalified) — 3-dehydroquinate synthase aroB aroA (requalified) — 3-phosphoshikimate 1-carboxyvinyltransferase aroA aroK (requalified) — shikimate kinase AroK aroK Rv2455c (family_assigned) — 2-oxoacid:acceptor oxidoreductase subunit alpha Rv2455c Rv0948c (requalified) — chorismate mutase Rv0948c Rv1885c (requalified) — chorismate mutase Rv1885c mltG (requalified) — endolytic transglycosylase MltG mltG aroD (requalified) — type II 3-dehydroquinate dehydratase aroD Rv2551c (family_assigned) — A24 family peptidase Rv2551c mbtK (requalified) — lysine N-acyltransferase MbtK mbtK irtB (family_assigned) — iron ABC transporter ATP-binding protein/permease irtB irtA (family_assigned) — iron ABC transporter ATP-binding protein/permease irtA

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.