MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2384 · 38 genes shown · anchor mbtB · open gene page → · ← back to 1 hop

Evidence: Min score 0
mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA mbtB (requalified) — phenyloxazoline synthase MbtB mbtB mbtI (requalified) — salicylate synthase mbtI pks13 (requalified) — polyketide synthase Pks13 pks13 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH entC (requalified) — isochorismate synthase entC mbtJ (requalified) — acetyl hydrolase mbtJ irtA (family_assigned) — iron ABC transporter ATP-binding protein/permease irtA mbtE (requalified) — peptide synthetase mbtE mbtF (requalified) — peptide synthetase mbtF mbtC (requalified) — polyketide synthetase MbtC mbtC Rv3839 (requalified) — DUF2470 domain-containing protein Rv3839 irtB (family_assigned) — iron ABC transporter ATP-binding protein/permease irtB pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 trpG (requalified) — anthranilate synthase component II trpG trpD (requalified) — anthranilate phosphoribosyltransferase trpD trpC (requalified) — indole-3-glycerol phosphate synthase TrpC trpC fas (requalified) — fatty acid synthase fas nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4 mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG menD (requalified) — 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1 menD aroF (requalified) — chorismate synthase aroF Rv2949c (family_assigned) — chorismate pyruvate-lyase family protein Rv2949c Rv3402c (family_assigned) — DegT/DnrJ/EryC1/StrS family aminotransferase Rv3402c lipI (family_assigned) — alpha/beta hydrolase lipI lipY (requalified) — triacylglycerol lipase Lip lipY Rv0435c (family_assigned) — AAA family ATPase Rv0435c mbtD (requalified) — mycobactin polyketide synthase MbtD mbtD pks17 (requalified) — polyketide synthase pks17 pks1 (requalified) — polyketide synthase pks1 PPE37 (family_assigned) — PPE family protein PPE37 PPE37 pheA (requalified) — prephenate dehydratase pheA Rv3837c (family_assigned) — histidine phosphatase family protein Rv3837c Rv0010c (family_assigned) — PH domain-containing protein Rv0010c Rv3840 (family_assigned) — transcriptional regulator Rv3840 dnaK (requalified) — molecular chaperone DnaK dnaK

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.