MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2382c · 33 genes shown · anchor mbtB · open gene page → · ← back to 1 hop

Evidence: Min score 0
mbtC (requalified) — polyketide synthetase MbtC mbtC mbtB (requalified) — phenyloxazoline synthase MbtB mbtB mbtE (requalified) — peptide synthetase mbtE mbtD (requalified) — mycobactin polyketide synthase MbtD mbtD mbtF (requalified) — peptide synthetase mbtF pks17 (requalified) — polyketide synthase pks17 pks1 (requalified) — polyketide synthase pks1 pks4 (requalified) — polyketide beta-ketoacyl synthase pks4 Rv3777 (requalified) — oxidoreductase Rv3777 fadB4 (family_assigned) — NADPH:quinone oxidoreductase family protein fadB4 fadB5 (family_assigned) — medium chain dehydrogenase/reductase family protei fadB5 mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG pks13 (requalified) — polyketide synthase Pks13 pks13 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 fas (requalified) — fatty acid synthase fas nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp pks8 (requalified) — polyketide synthase pks8 pks9 (requalified) — type I polyketide synthase pks9 pks15 (requalified) — polyketide synthase pks15 pks3 (requalified) — polyketide beta-ketoacyl synthase pks3 pks12 (requalified) — type I polyketide synthase pks12 fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD papA3 (requalified) — acyltransferase PapA3 papA3 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC Rv3776 (family_assigned) — hypothetical protein Rv3776 htdZ (requalified) — 3-hydroxyacyl-thioester dehydratase HtdZ htdZ fadE23 (family_assigned) — acyl-CoA dehydrogenase family protein fadE23 pks6 (requalified) — membrane bound polyketide synthase pks6 mbtI (requalified) — salicylate synthase mbtI entC (requalified) — isochorismate synthase entC mbtJ (requalified) — acetyl hydrolase mbtJ

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.