MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2381c · 39 genes shown · anchor mbtC · open gene page → · ← back to 1 hop

Evidence: Min score 0
mbtD (requalified) — mycobactin polyketide synthase MbtD mbtD mbtC (requalified) — polyketide synthetase MbtC mbtC mbtB (requalified) — phenyloxazoline synthase MbtB mbtB mbtE (requalified) — peptide synthetase mbtE mbtF (requalified) — peptide synthetase mbtF mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp pks15 (requalified) — polyketide synthase pks15 mbtI (requalified) — salicylate synthase mbtI pks3 (requalified) — polyketide beta-ketoacyl synthase pks3 tesA (requalified) — thioesterase TesA tesA mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC pks17 (requalified) — polyketide synthase pks17 pks1 (requalified) — polyketide synthase pks1 pks13 (requalified) — polyketide synthase Pks13 pks13 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 fas (requalified) — fatty acid synthase fas fadD10 (requalified) — fatty-acid--CoA ligase FadD10 fadD10 pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 mas (requalified) — mycocerosate synthase mas fadD29 (requalified) — long-chain-fatty-acid--AMP ligase FadD29 fadD29 fadD22 (requalified) — p-hydroxybenzoic acid--AMP ligase FadD22 fadD22 pks4 (requalified) — polyketide beta-ketoacyl synthase pks4 Rv2949c (family_assigned) — chorismate pyruvate-lyase family protein Rv2949c trpG (requalified) — anthranilate synthase component II trpG trpD (requalified) — anthranilate phosphoribosyltransferase trpD trpC (requalified) — indole-3-glycerol phosphate synthase TrpC trpC entC (requalified) — isochorismate synthase entC papA3 (requalified) — acyltransferase PapA3 papA3 Rv3777 (requalified) — oxidoreductase Rv3777 fadB4 (family_assigned) — NADPH:quinone oxidoreductase family protein fadB4 ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB ppsA (requalified) — phthiocerol type I polyketide synthase PpsA ppsA ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD mbtJ (requalified) — acetyl hydrolase mbtJ fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.