MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2378c · 41 genes shown · anchor mbtF · open gene page → · ← back to 1 hop

Evidence: Min score 0
mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtF (requalified) — peptide synthetase mbtF mbtE (requalified) — peptide synthetase mbtE mbtB (requalified) — phenyloxazoline synthase MbtB mbtB mbtD (requalified) — mycobactin polyketide synthase MbtD mbtD mbtC (requalified) — polyketide synthetase MbtC mbtC irtB (family_assigned) — iron ABC transporter ATP-binding protein/permease irtB mbtK (requalified) — lysine N-acyltransferase MbtK mbtK Rv0955 (family_assigned) — DUF6350 family protein Rv0955 PPE2 (family_assigned) — PPE family protein PPE2 PPE2 aftD (family_assigned) — DUF3367 domain-containing protein aftD Rv3604c (dark) — DUF6779 domain-containing protein Rv3604c pks13 (requalified) — polyketide synthase Pks13 pks13 nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fas (requalified) — fatty acid synthase fas mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 pks17 (requalified) — polyketide synthase pks17 pks1 (requalified) — polyketide synthase pks1 irtA (family_assigned) — iron ABC transporter ATP-binding protein/permease irtA dnaK (requalified) — molecular chaperone DnaK dnaK Rv3402c (family_assigned) — DegT/DnrJ/EryC1/StrS family aminotransferase Rv3402c Rv0923c (family_assigned) — poly-gamma-glutamate hydrolase family protein Rv0923c rnc (requalified) — ribonuclease III rnc Rv0954 (requalified) — DUF5336 domain-containing protein Rv0954 purN (requalified) — phosphoribosylglycinamide formyltransferase purN purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH pimE (requalified) — mannosyltransferase pimE cobQ1 (requalified) — cobyric acid synthase cobQ1 pirG (requalified) — exported repetitive protein pirG eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c Rv0479c (family_assigned) — DUF2993 domain-containing protein Rv0479c aftC (requalified) — arabinofuranan 3-O-arabinosyltransferase aftC Rv0224c (requalified) — class I SAM-dependent methyltransferase Rv0224c mmpA (requalified) — hypothetical protein mmpA Rv0227c (family_assigned) — membrane protein Rv0227c Rv3605c (family_assigned) — DUF3180 domain-containing protein Rv3605c rsmA (requalified) — anti-sigma-M factor RsmA rsmA Rv0804 (family_assigned) — CPBP family intramembrane glutamic endopeptidase Rv0804

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.