MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2377c · 36 genes shown · anchor pks13 · open gene page → · ← back to 1 hop

Evidence: Min score 0
mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH pks13 (requalified) — polyketide synthase Pks13 pks13 mbtE (requalified) — peptide synthetase mbtE mbtB (requalified) — phenyloxazoline synthase MbtB mbtB mbtF (requalified) — peptide synthetase mbtF mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA papA1 (requalified) — acyltransferase PapA1 papA1 papA3 (requalified) — acyltransferase PapA3 papA3 papA2 (requalified) — trehalose-2-sulfate acyltransferase papA2 tesA (requalified) — thioesterase TesA tesA mbtC (requalified) — polyketide synthetase MbtC mbtC fas (requalified) — fatty acid synthase fas fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4 pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 mbtD (requalified) — mycobactin polyketide synthase MbtD mbtD fadD10 (requalified) — fatty-acid--CoA ligase FadD10 fadD10 pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 mas (requalified) — mycocerosate synthase mas mbtI (requalified) — salicylate synthase mbtI entC (requalified) — isochorismate synthase entC mbtJ (requalified) — acetyl hydrolase mbtJ mmpL8 (requalified) — sulfolipid-1 RND transporter MmpL8 mmpL8 pks12 (requalified) — type I polyketide synthase pks12 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC pks4 (requalified) — polyketide beta-ketoacyl synthase pks4 mmpL10 (requalified) — RND transporter MmpL10 mmpL10 pks3 (requalified) — polyketide beta-ketoacyl synthase pks3 ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB ppsA (requalified) — phthiocerol type I polyketide synthase PpsA ppsA ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD pks17 (requalified) — polyketide synthase pks17 pks1 (requalified) — polyketide synthase pks1

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.