MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2374c · 41 genes shown · anchor dnaJ2 · open gene page → · ← back to 1 hop

Evidence: Min score 0
hrcA (requalified) — heat-inducible transcriptional repressor HrcA hrcA dnaJ2 (requalified) — molecular chaperone DnaJ dnaJ2 grpE (requalified) — nucleotide exchange factor GrpE grpE Rv2372c (requalified) — 16S rRNA (uracil(1498)-N(3))-methyltransferase Rv2372c Rv2375 (family_assigned) — type II toxin-antitoxin system VapB family antitox Rv2375 dnaJ1 (requalified) — chaperone protein DnaJ dnaJ1 Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c clpP1 (family_assigned) — ATP-dependent CLP protease proteolytic subunit 1 clpP1 Rv2264c (family_assigned) — Hsp70 family protein Rv2264c dnaK (requalified) — molecular chaperone DnaK dnaK clpP2 (family_assigned) — ATP-dependent CLP protease proteolytic subunit Clp clpP2 Rv0312 (family_assigned) — Hsp70 family protein Rv0312 phoP (requalified) — two-component system response regulator PhoP phoP htpG (requalified) — molecular chaperone HtpG htpG hspR (family_assigned) — heat shock transcriptional regulator HspR hspR clpB (requalified) — chaperone protein ClpB clpB groEL2 (requalified) — chaperonin GroEL groEL2 era (requalified) — GTPase Era era Rv2365c (requalified) — cytidine deaminase Rv2365c Rv2366c (family_assigned) — hemolysin family protein Rv2366c Rv2367c (requalified) — endoribonuclease Rv2367c disA (requalified) — DNA integrity scanning diadenylate cyclase DisA disA Rv1929c (family_assigned) — TIGR03085 family metal-binding protein Rv1929c Rv2466c (family_assigned) — Rv2466c family mycothiol-dependent reductase Rv2466c eccD4 (family_assigned) — type VII secretion system ESX-4 subunit EccD4 eccD4 eccC4 (family_assigned) — type VII secretion system ESX-4 FtsK/SpoIIIE famil eccC4 mycP4 (requalified) — type VII secretion system ESX-4 serine protease my mycP4 clpX (family_assigned) — ATP-dependent Clp protease ATP-binding subunit Clp clpX tig (requalified) — trigger factor tig clpC1 (family_assigned) — ATP-dependent protease ATP-binding subunit ClpC clpC1 groES (requalified) — chaperonin GroES groES groEL1 (requalified) — chaperonin GroEL groEL1 Rv3716c (family_assigned) — YbaB/EbfC family nucleoid-associated protein Rv3716c pirG (requalified) — exported repetitive protein pirG Rv2721c (family_assigned) — LGFP repeat-containing protein Rv2721c phoR (requalified) — sensory box histidine kinase PhoR phoR Rv0600c (requalified) — two component sensor kinase HK1 Rv0600c prrB (requalified) — two-component system sensor histidine kinase PrrB prrB trcS (family_assigned) — HAMP domain-containing sensor histidine kinase trcS tcrY (requalified) — two component sensor kinase TcrY tcrY senX3 (requalified) — two-component system sensor histidine kinase SenX3 senX3

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.