MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2315c · 46 genes shown · anchor uspC · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv2315c (family_assigned) — TldD/PmbA family protein Rv2315c Rv2314c (family_assigned) — TldD/PmbA family protein Rv2314c Rv2313c (family_assigned) — carboxymuconolactone decarboxylase family protein Rv2313c uspC (family_assigned) — sugar ABC transporter substrate-binding protein uspC uspA (family_assigned) — sugar ABC transporter permease uspA uspB (family_assigned) — sugar ABC transporter permease UspB uspB Rv1473A (family_assigned) — transcriptional regulator Rv1473A desA2 (requalified) — acyl-ACP desaturase desA2 etgB (requalified) — ergothioneine biosynthesis protein EgtB etgB pyrF (requalified) — orotidine-5'-phosphate decarboxylase pyrF lpdA (requalified) — NAD(P)H-quinone dehydrogenase lpdA gpm1 (requalified) — 2,3-bisphosphoglycerate-dependent phosphoglycerate gpm1 end (requalified) — deoxyribonuclease IV end cysC (requalified) — adenylyl-sulfate kinase cysC Rv2039c (family_assigned) — carbohydrate ABC transporter permease Rv2039c Rv2040c (family_assigned) — sugar ABC transporter permease Rv2040c ugpC (family_assigned) — ABC transporter ATP-binding protein ugpC ugpC (family_assigned) — sn-glycerol-3-phosphate ABC transporter ATP-bindin ugpC sugC (family_assigned) — trehalose ABC transporter ATP-binding protein SugC sugC ugpE (family_assigned) — carbohydrate ABC transporter permease ugpE ugpA (family_assigned) — sugar ABC transporter permease ugpA Rv1473 (family_assigned) — macrolide ABC transporter ATP-binding protein Rv1473 echA12 (requalified) — enoyl-CoA hydratase echA12 rsbW (requalified) — anti-sigma B factor RsbW rsbW Rv2709 (dark) — DUF3099 domain-containing protein Rv2709 Rv2844 (family_assigned) — ferritin-like domain-containing protein Rv2844 desA1 (requalified) — acyl-ACP desaturase DesA desA1 Rv3230c (requalified) — NADPH oxidoreductase Rv3230c desA3 (requalified) — stearoyl-CoA 9-desaturase desA3 fas (requalified) — fatty acid synthase fas nrdI (requalified) — class Ib ribonucleoside-diphosphate reductase asse nrdI fdxC (family_assigned) — ferredoxin family protein fdxC egtD (requalified) — L-histidine N(alpha)-methyltransferase egtD egtC (requalified) — ergothioneine biosynthesis protein EgtC egtC gshA (requalified) — ergothioneine biosynthesis glutamate--cysteine lig gshA egtE (requalified) — ergothioneine biosynthesis PLP-dependent enzyme Eg egtE Rv3705c (family_assigned) — sensor domain-containing protein Rv3705c Rv0433 (requalified) — glutamate--cysteine ligase Rv0433 carB (family_assigned) — carbamoyl-phosphate synthase large subunit carB pyrR (family_assigned) — bifunctional pyr operon transcriptional regulator/ pyrR carA (family_assigned) — glutamine-hydrolyzing carbamoyl-phosphate synthase carA pyrC (requalified) — dihydroorotase pyrC pyrB (family_assigned) — aspartate carbamoyltransferase catalytic subunit pyrB pyrE (requalified) — orotate phosphoribosyltransferase pyrE Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c glpD2 (requalified) — glycerol-3-phosphate dehydrogenase/oxidase glpD2

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.