MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2276 · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
cyp121 (requalified) — mycocyclosin synthase Cyp121 cyp121 Rv2275 (requalified) — cyclo(L-tyrosyl-L-tyrosyl) synthase Rv2275 pks13 (requalified) — polyketide synthase Pks13 pks13 Rv1937 (requalified) — FAD-binding oxidoreductase Rv1937 mbtE (requalified) — peptide synthetase mbtE Rv2776c (requalified) — oxidoreductase Rv2776c rplF (requalified) — 50S ribosomal protein L6 rplF cyp137 (requalified) — cytochrome P450 cyp137 polA (requalified) — DNA polymerase I polA pks1 (requalified) — polyketide synthase pks1 fdxB (requalified) — fatty acid desaturase fdxB ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB pks12 (requalified) — type I polyketide synthase pks12 PE_PGRS28 (family_assigned) — PE-PGRS family protein PE_PGRS28 PE_PGRS28 PE_PGRS43 (family_assigned) — PE-PGRS family protein PE_PGRS43 PE_PGRS43 PPE8 (family_assigned) — PPE family protein PPE8 PPE8 PPE56 (family_assigned) — PPE family protein PPE56 PPE56 PPE55 (family_assigned) — PPE family protein PPE55 PPE55 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtB (requalified) — phenyloxazoline synthase MbtB mbtB fas (requalified) — fatty acid synthase fas nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4 fadH (requalified) — NADPH-dependent 2%2C4-dienoyl-CoA reductase fadH fprB (requalified) — FAD-dependent oxidoreductase fprB fprA (requalified) — ferredoxin--NADP(+) reductase FprA fprA gltD (family_assigned) — glutamate synthase subunit beta gltD ephB (requalified) — epoxide hydrolase EphB ephB ribA1 (requalified) — riboflavin biosynthesis protein RibA ribA1 mbtC (requalified) — polyketide synthetase MbtC mbtC mbtF (requalified) — peptide synthetase mbtF mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG cyp123 (requalified) — cytochrome P450 cyp123 cyp142 (requalified) — steroid C26-monooxygenase Cyp142 cyp142 Rv2777c (requalified) — metal-dependent hydrolase Rv2777c Rv1465 (family_assigned) — SUF system NifU family Fe-S cluster assembly prote Rv1465 iscS (family_assigned) — cysteine desulfurase family protein iscS cyp141 (requalified) — cytochrome P450 Cyp141 cyp141 rpsD (requalified) — 30S ribosomal protein S4 rpsD rplW (requalified) — 50S ribosomal protein L23 rplW rpsG (requalified) — 30S ribosomal protein S7 rpsG rplS (requalified) — 50S ribosomal protein L19 rplS rpsR1 (requalified) — 30S ribosomal protein S18 rpsR1 rplB (requalified) — 50S ribosomal protein L2 rplB Rv3686c (dark) — hypothetical protein Rv3686c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.