MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2268c · 46 genes shown · anchor cyp139 · open gene page → · ← back to 1 hop

Evidence: Min score 0
cyp128 (requalified) — cytochrome P450 cyp128 Rv2267c (requalified) — sulfotransferase Rv2267c pks13 (requalified) — polyketide synthase Pks13 pks13 Rv1937 (requalified) — FAD-binding oxidoreductase Rv1937 mbtE (requalified) — peptide synthetase mbtE Rv2269c (family_assigned) — hypothetical protein Rv2269c Rv2776c (requalified) — oxidoreductase Rv2776c cyp139 (requalified) — cytochrome P450 cyp139 cyp132 (requalified) — cytochrome P450 Cyp132 cyp132 rplF (requalified) — 50S ribosomal protein L6 rplF polA (requalified) — DNA polymerase I polA pks1 (requalified) — polyketide synthase pks1 fdxB (requalified) — fatty acid desaturase fdxB htpG (requalified) — molecular chaperone HtpG htpG alaS (requalified) — alanine--tRNA ligase alaS rpoA (family_assigned) — DNA-directed RNA polymerase subunit alpha rpoA mftF (requalified) — mycofactocin biosynthesis glycosyltransferase MftF mftF rpoZ (family_assigned) — DNA-directed RNA polymerase subunit omega rpoZ mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtB (requalified) — phenyloxazoline synthase MbtB mbtB fas (requalified) — fatty acid synthase fas nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4 fadH (requalified) — NADPH-dependent 2%2C4-dienoyl-CoA reductase fadH fprB (requalified) — FAD-dependent oxidoreductase fprB fprA (requalified) — ferredoxin--NADP(+) reductase FprA fprA gltD (family_assigned) — glutamate synthase subunit beta gltD ephB (requalified) — epoxide hydrolase EphB ephB ribA1 (requalified) — riboflavin biosynthesis protein RibA ribA1 mbtC (requalified) — polyketide synthetase MbtC mbtC mbtF (requalified) — peptide synthetase mbtF mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG lppN (family_assigned) — hypothetical protein lppN cyp124 (requalified) — methyl-branched lipid omega-hydroxylase Cyp124 cyp124 cyp123 (requalified) — cytochrome P450 cyp123 cyp142 (requalified) — steroid C26-monooxygenase Cyp142 cyp142 Rv2777c (requalified) — metal-dependent hydrolase Rv2777c Rv1465 (family_assigned) — SUF system NifU family Fe-S cluster assembly prote Rv1465 iscS (family_assigned) — cysteine desulfurase family protein iscS cyp141 (requalified) — cytochrome P450 Cyp141 cyp141 Rv1667c (family_assigned) — Probable second part of macrolide-transport ATP-bi Rv1667c Rv1668c (family_assigned) — Probable first part of macrolide-transport ATP-bin Rv1668c Rv1393c (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv1393c Rv1395 (family_assigned) — HTH-type transcriptional regulator Rv1395 rpsD (requalified) — 30S ribosomal protein S4 rpsD

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.