MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2243 · 35 genes shown · anchor kasA · open gene page → · ← back to 1 hop

Evidence: Min score 0
fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD kasA (requalified) — 3-oxoacyl-ACP synthase KasA kasA kasB (requalified) — 3-oxoacyl-ACP synthase 2 kasB pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 mas (requalified) — mycocerosate synthase mas pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 pks12 (requalified) — type I polyketide synthase pks12 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC accD6 (family_assigned) — acyl-CoA carboxylase subunit beta accD6 acpM (requalified) — meromycolate extension acyl carrier protein AcpM acpM pks13 (requalified) — polyketide synthase Pks13 pks13 fas (requalified) — fatty acid synthase fas pks1 (requalified) — polyketide synthase pks1 accD3 (family_assigned) — carboxyl transferase domain-containing protein accD3 fabH (requalified) — beta-ketoacyl-ACP synthase III fabH mbtB (requalified) — phenyloxazoline synthase MbtB mbtB papA1 (requalified) — acyltransferase PapA1 papA1 ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB accA3 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA3 accA1 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA1 accA2 (family_assigned) — biotin carboxylase N-terminal domain-containing pr accA2 embB (requalified) — arabinosyltransferase EmbB embB embC (requalified) — arabinosyltransferase EmbC embC embA (requalified) — arabinosyltransferase EmbA embA mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4 pks7 (requalified) — type I polyketide synthase pks7 pks17 (requalified) — polyketide synthase pks17 pks6 (requalified) — membrane bound polyketide synthase pks6 pks15 (requalified) — polyketide synthase pks15 mbtC (requalified) — polyketide synthetase MbtC mbtC

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.