MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2237 · 46 genes shown · anchor cobD · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv2237 (family_assigned) — hypothetical protein Rv2237 cobD (requalified) — cobalamin biosynthesis protein cobD Rv0825c (family_assigned) — TetR/AcrR family transcriptional regulator Rv0825c Rv0275c (family_assigned) — transcriptional regulator Rv0275c Rv1645c (family_assigned) — oxygenase MpaB family protein Rv1645c Rv1429 (family_assigned) — PucR family transcriptional regulator Rv1429 Rv2620c (dark) — hypothetical protein Rv2620c Rv1683 (requalified) — acyl-CoA synthetase Rv1683 Rv1132 (family_assigned) — DUF3556 domain-containing protein Rv1132 cobN (family_assigned) — cobaltochelatase subunit CobN cobN cobU (requalified) — bifunctional adenosylcobinamide kinase/adenosylcob cobU cobQ1 (requalified) — cobyric acid synthase cobQ1 cobO (requalified) — cob(I)alamin adenosyltransferase cobO Rv1314c (requalified) — cob(I)yrinic acid a%2Cc-diamide adenosyltransferas Rv1314c cobH (requalified) — precorrin-8X methylmutase cobH cobB (requalified) — cobyrinate a%2Cc-diamide synthase cobB Rv0826 (family_assigned) — oxygenase MpaB family protein Rv0826 desA1 (requalified) — acyl-ACP desaturase DesA desA1 dusB (requalified) — tRNA dihydrouridine synthase DusB dusB Rv0276 (family_assigned) — oxygenase MpaB family protein Rv0276 Rv1152 (family_assigned) — GntR family transcriptional regulator Rv1152 Rv0875c (dark) — DUF2771 domain-containing protein Rv0875c Rv1171 (family_assigned) — hypothetical protein Rv1171 adnA (requalified) — ATP-dependent DNA helicase AdnA adnA Rv0048c (family_assigned) — DUF1707 domain-containing protein Rv0048c Rv1647 (requalified) — adenylate cyclase Rv1647 Rv0910 (family_assigned) — SRPBCC family protein Rv0910 Rv1919c (family_assigned) — SRPBCC family protein Rv1919c Rv0135c (family_assigned) — helix-turn-helix domain-containing protein Rv0135c Rv1431 (family_assigned) — DUF3556 domain-containing protein Rv1431 Rv1428c (family_assigned) — lysophospholipid acyltransferase family protein Rv1428c fadD12 (requalified) — acyl-CoA ligase FadD12 fadD12 lipO (family_assigned) — alpha/beta hydrolase lipO Rv2113 (family_assigned) — integral membrane protein Rv2113 ptrp (family_assigned) — hypothetical protein ptrp Rv2619c (family_assigned) — cupin domain-containing protein Rv2619c Rv2621c (family_assigned) — helix-turn-helix domain-containing protein Rv2621c Rv2622 (family_assigned) — methyltransferase domain-containing protein Rv2622 fdxA (family_assigned) — ferredoxin family protein fdxA TB31.7 (requalified) — universal stress protein TB31.7 TB31.7 Rv0185 (family_assigned) — TIGR04338 family metallohydrolase Rv0185 Rv1684 (family_assigned) — Trm112 family protein Rv1684 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC mas (requalified) — mycocerosate synthase mas pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 pks12 (requalified) — type I polyketide synthase pks12

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.