MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2214c · 46 genes shown · anchor pks12 · open gene page → · ← back to 1 hop

Evidence: Min score 0
ephD (family_assigned) — SDR family oxidoreductase ephD pks12 (requalified) — type I polyketide synthase pks12 mas (requalified) — mycocerosate synthase mas pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 Rv3549c (family_assigned) — SDR family oxidoreductase Rv3549c pks1 (requalified) — polyketide synthase pks1 Rv2777c (requalified) — metal-dependent hydrolase Rv2777c Rv2216 (family_assigned) — TIGR01777 family oxidoreductase Rv2216 pks4 (requalified) — polyketide beta-ketoacyl synthase pks4 dlaT (requalified) — 2-oxoglutarate dehydrogenase%2C E2 component%2C di dlaT pks7 (requalified) — type I polyketide synthase pks7 fas (requalified) — fatty acid synthase fas fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD mbtB (requalified) — phenyloxazoline synthase MbtB mbtB papA1 (requalified) — acyltransferase PapA1 papA1 ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB echA20 (family_assigned) — enoyl-CoA hydratase family protein echA20 Rv3548c (family_assigned) — SDR family oxidoreductase Rv3548c Rv3552 (family_assigned) — CoA-transferase subunit beta Rv3552 Rv3551 (family_assigned) — CoA transferase subunit A Rv3551 Rv3553 (requalified) — nitronate monooxygenase Rv3553 pks15 (requalified) — polyketide synthase pks15 mbtC (requalified) — polyketide synthetase MbtC mbtC Rv2776c (requalified) — oxidoreductase Rv2776c Rv2778c (family_assigned) — SRPBCC family protein Rv2778c desA3 (requalified) — stearoyl-CoA 9-desaturase desA3 Rv3434c (family_assigned) — rhomboid-like protein Rv3434c Rv2300c (requalified) — metallo-hydrolase Rv2300c lipB (requalified) — lipoyl(octanoyl) transferase LipB lipB lipA (requalified) — lipoyl synthase lipA Rv2219 (family_assigned) — DUF4191 domain-containing protein Rv2219 arcA (requalified) — arginine deiminase arcA pks3 (requalified) — polyketide beta-ketoacyl synthase pks3 papA3 (requalified) — acyltransferase PapA3 papA3 lpdC (requalified) — dihydrolipoyl dehydrogenase lpdC Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c bkdB (family_assigned) — 3-methyl-2-oxobutanoate dehydrogenase subunit beta bkdB aceE (requalified) — pyruvate dehydrogenase E1 component aceE sucC (family_assigned) — ADP-forming succinate--CoA ligase subunit beta sucC bkdA (family_assigned) — pyruvate dehydrogenase (acetyl-transferring) E1 co bkdA pks8 (requalified) — polyketide synthase pks8 pks9 (requalified) — type I polyketide synthase pks9

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.