MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2210c · 46 genes shown · anchor gcvT · open gene page → · ← back to 1 hop

Evidence: Min score 0
ilvE (requalified) — branched-chain amino acid aminotransferase ilvE ilvD (requalified) — dihydroxy-acid dehydratase ilvD leuA (requalified) — 2-isopropylmalate synthase leuA metB (requalified) — cystathionine gamma-synthase metB aspC (requalified) — pyridoxal phosphate-dependent aminotransferase aspC panB (requalified) — 3-methyl-2-oxobutanoate hydroxymethyltransferase panB gshA (requalified) — ergothioneine biosynthesis glutamate--cysteine lig gshA ilvA (requalified) — threonine ammonia-lyase ilvA thrA (requalified) — homoserine dehydrogenase thrA thrB (requalified) — homoserine kinase thrB gcvT (requalified) — aminomethyltransferase gcvT Rv2212 (requalified) — adenylyl cyclase Rv2212 pepB (requalified) — leucyl aminopeptidase pepB ilvC (requalified) — ketol-acid reductoisomerase ilvC ilvB1 (family_assigned) — acetolactate synthase large subunit IlvB ilvB1 leuC (family_assigned) — 3-isopropylmalate dehydratase large subunit leuC hsaG (requalified) — acetaldehyde dehydrogenase (acetylating) hsaG leuD (family_assigned) — 3-isopropylmalate dehydratase small subunit leuD accA3 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA3 cbs (requalified) — cystathionine beta-synthase cbs metH (requalified) — methionine synthase metH cysK1 (requalified) — O-acetylserine sulfhydrylase cysK1 Rv3684 (requalified) — lyase Rv3684 metE (requalified) — 5-methyltetrahydropteroyltriglutamate--homocystein metE metC (requalified) — bifunctional o-acetylhomoserine/o-acetylserine sul metC argJ (requalified) — bifunctional glutamate N-acetyltransferase/amino-a argJ gdh (requalified) — NAD-glutamate dehydrogenase gdh ald (requalified) — alanine dehydrogenase ald panC (requalified) — pantoate--beta-alanine ligase panC panD (requalified) — aspartate 1-decarboxylase panD Rv2573 (requalified) — 2-dehydropantoate 2-reductase Rv2573 Rv2226 (family_assigned) — CYTH and CHAD domain-containing protein Rv2226 etgB (requalified) — ergothioneine biosynthesis protein EgtB etgB egtC (requalified) — ergothioneine biosynthesis protein EgtC egtC egtD (requalified) — L-histidine N(alpha)-methyltransferase egtD Rv0433 (requalified) — glutamate--cysteine ligase Rv0433 ggtB (family_assigned) — gamma-glutamyltransferase family protein ggtB ggtA (requalified) — bifunctional cephalosporin acylase/gamma-glutamylt ggtA ilvN (family_assigned) — acetolactate synthase small subunit ilvN leuB (requalified) — 3-isopropylmalate dehydrogenase leuB thrC (requalified) — threonine synthase thrC ilvB2 (family_assigned) — thiamine pyrophosphate-binding protein ilvB2 ilvG (requalified) — acetolactate synthase ilvG asd (requalified) — aspartate-semialdehyde dehydrogenase asd metA (requalified) — homoserine O-acetyltransferase metA dapA (requalified) — 4-hydroxy-tetrahydrodipicolinate synthase dapA

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.