MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2124c · 40 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
metH (requalified) — methionine synthase metH Rv2172c (requalified) — mycobacterial-type methylenetetrahydrofolate reduc Rv2172c metB (requalified) — cystathionine gamma-synthase metB metZ (requalified) — O-succinylhomoserine sulfhydrylase metZ metE (requalified) — 5-methyltetrahydropteroyltriglutamate--homocystein metE metC (requalified) — bifunctional o-acetylhomoserine/o-acetylserine sul metC sahH (requalified) — adenosylhomocysteinase sahH gcvT (requalified) — aminomethyltransferase gcvT metK (requalified) — S-adenosylmethionine synthetase metK metS (requalified) — methionine--tRNA ligase metS thrA (requalified) — homoserine dehydrogenase thrA cbs (requalified) — cystathionine beta-synthase cbs mmuM (requalified) — homocysteine S-methyltransferase mmuM Rv3015c (requalified) — methionine synthase Rv3015c idsA2 (requalified) — bifunctional (2E%2C6E)-farnesyl/geranyl diphosphat idsA2 cysK1 (requalified) — O-acetylserine sulfhydrylase cysK1 Rv3684 (requalified) — lyase Rv3684 metA (requalified) — homoserine O-acetyltransferase metA Rv3342 (requalified) — class I SAM-dependent methyltransferase Rv3342 mtn (requalified) — 5'-methylthioadenosine/adenosylhomocysteine nucleo mtn gcvH (requalified) — glycine cleavage system protein GcvH gcvH gcvB (requalified) — aminomethyl-transferring glycine dehydrogenase gcvB glyA2 (requalified) — serine hydroxymethyltransferase glyA2 glyA1 (requalified) — serine hydroxymethyltransferase glyA1 lpdC (requalified) — dihydrolipoyl dehydrogenase lpdC folD (requalified) — bifunctional methylenetetrahydrofolate dehydrogena folD ribH (requalified) — 6%2C7-dimethyl-8-ribityllumazine synthase ribH mscL (requalified) — large-conductance mechanosensitive channel protein mscL gmk (requalified) — guanylate kinase gmk gltS (requalified) — glutamate--tRNA ligase gltS leuS (requalified) — leucine--tRNA ligase leuS tatD (requalified) — deoxyribonuclease TatD tatD argS (requalified) — arginine--tRNA ligase argS ileS (requalified) — isoleucine--tRNA ligase ileS thrB (requalified) — homoserine kinase thrB thrC (requalified) — threonine synthase thrC asd (requalified) — aspartate-semialdehyde dehydrogenase asd dapA (requalified) — 4-hydroxy-tetrahydrodipicolinate synthase dapA lysA (requalified) — diaminopimelate decarboxylase lysA cysE (requalified) — serine O-acetyltransferase cysE

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.