MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2123 · 45 genes shown · anchor hisE · open gene page → · ← back to 1 hop

Evidence: Min score 0
PPE37 (family_assigned) — PPE family protein PPE37 PPE37 Rv3839 (requalified) — DUF2470 domain-containing protein Rv3839 mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA hisE (requalified) — phosphoribosyl-ATP pyrophosphatase hisE hisG (requalified) — ATP phosphoribosyltransferase hisG Rv2120c (family_assigned) — glycine zipper 2TM domain-containing protein Rv2120c irtA (family_assigned) — iron ABC transporter ATP-binding protein/permease irtA PE5 (family_assigned) — PE family protein PE5 PE5 eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 esxG (requalified) — type VII secretion system protein EsxG esxG Rv3402c (family_assigned) — DegT/DnrJ/EryC1/StrS family aminotransferase Rv3402c eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 eccE3 (family_assigned) — type VII secretion system ESX-3 subunit EccE3 eccE3 pheA (requalified) — prephenate dehydratase pheA Rv3837c (family_assigned) — histidine phosphatase family protein Rv3837c Rv0010c (family_assigned) — PH domain-containing protein Rv0010c Rv3840 (family_assigned) — transcriptional regulator Rv3840 mbtB (requalified) — phenyloxazoline synthase MbtB mbtB mbtI (requalified) — salicylate synthase mbtI pks13 (requalified) — polyketide synthase Pks13 pks13 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH entC (requalified) — isochorismate synthase entC mbtJ (requalified) — acetyl hydrolase mbtJ hisI (requalified) — phosphoribosyl-AMP cyclohydrolase hisI hisF (family_assigned) — imidazole glycerol phosphate synthase subunit HisF hisF hisD (requalified) — histidinol dehydrogenase hisD hisH (family_assigned) — imidazole glycerol phosphate synthase subunit HisH hisH hisA (requalified) — bifunctional 1-(5-phosphoribosyl)-5-((5-phosphorib hisA hisB (requalified) — imidazoleglycerol-phosphate dehydratase HisB hisB pirG (requalified) — exported repetitive protein pirG Rv3707c (requalified) — hypothetical protein Rv3707c Rv0315 (requalified) — family 16 glycosylhydrolase Rv0315 Rv2743c (family_assigned) — hypothetical protein Rv2743c irtB (family_assigned) — iron ABC transporter ATP-binding protein/permease irtB Rv0435c (family_assigned) — AAA family ATPase Rv0435c eccA3 (requalified) — ESX-3 secretion system protein EccA eccA3 eccC3 (family_assigned) — type VII secretion system ESX-3 FtsK/SpoIIIE famil eccC3 PPE4 (family_assigned) — PPE family protein PPE4 PPE4 espG3 (requalified) — type VII secretion system ESX-3 associated protein espG3 mycP3 (requalified) — type VII secretion system ESX-3 serine protease my mycP3 esxH (requalified) — type VII secretion system effector EsxH esxH esxR (family_assigned) — WXG100 family type VII secretion target esxR esxQ (requalified) — type VII secretion system ESX-3 effector EsxQ esxQ mbtK (requalified) — lysine N-acyltransferase MbtK mbtK eccB5 (family_assigned) — type VII secretion system ESX-5 subunit EccB5 eccB5

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.