MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2121c · 32 genes shown · anchor hisE · open gene page → · ← back to 1 hop

Evidence: Min score 0
hisG (requalified) — ATP phosphoribosyltransferase hisG hisE (requalified) — phosphoribosyl-ATP pyrophosphatase hisE hisD (requalified) — histidinol dehydrogenase hisD hisB (requalified) — imidazoleglycerol-phosphate dehydratase HisB hisB hisH (family_assigned) — imidazole glycerol phosphate synthase subunit HisH hisH hisF (family_assigned) — imidazole glycerol phosphate synthase subunit HisF hisF hisI (requalified) — phosphoribosyl-AMP cyclohydrolase hisI hisA (requalified) — bifunctional 1-(5-phosphoribosyl)-5-((5-phosphorib hisA hisC1 (requalified) — histidinol-phosphate aminotransferase hisC1 prsA (requalified) — ribose-phosphate diphosphokinase prsA hisS (requalified) — histidine--tRNA ligase hisS cobC (requalified) — aminotransferase cobC Rv2120c (family_assigned) — glycine zipper 2TM domain-containing protein Rv2120c bkdB (family_assigned) — 3-methyl-2-oxobutanoate dehydrogenase subunit beta bkdB Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c glmU (requalified) — bifunctional UDP-N-acetylglucosamine diphosphoryla glmU tkt (requalified) — transketolase tkt rbsK (requalified) — ribokinase RbsK rbsK purF (requalified) — amidophosphoribosyltransferase purF Rv2581c (requalified) — MBL fold metallo-hydrolase Rv2581c aspS (requalified) — aspartate--tRNA ligase aspS valS (requalified) — valine--tRNA ligase valS gcpE (requalified) — flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-e gcpE ppiB (requalified) — peptidyl-prolyl cis-trans isomerase B ppiB Rv2230c (requalified) — Nif3-like dinuclear metal center hexameric protein Rv2230c tyrA (requalified) — prephenate dehydrogenase TyrA tyrA cobB (requalified) — cobyrinate a%2Cc-diamide synthase cobB cobQ1 (requalified) — cobyric acid synthase cobQ1 pirG (requalified) — exported repetitive protein pirG Rv3707c (requalified) — hypothetical protein Rv3707c Rv0315 (requalified) — family 16 glycosylhydrolase Rv0315 Rv2743c (family_assigned) — hypothetical protein Rv2743c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.