Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2114 · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv2114 (dark) — hypothetical protein Rv2114 Rv2113 (family_assigned) — integral membrane protein Rv2113 Rv1006 (family_assigned) — hypothetical protein Rv1006 Rv1868 (family_assigned) — NAD(P)H-binding protein Rv1868 hsr1 (requalified) — hypothetical protein hsr1 Rv2047c (family_assigned) — sugar epimerase family protein Rv2047c Rv3033 (requalified) — DUF4333 domain-containing protein Rv3033 Rv0180c (family_assigned) — YhgE/Pip domain-containing protein Rv0180c dop (requalified) — pup deamidase/depupylase dop eccD5 (family_assigned) — type VII secretion system ESX-5 subunit EccD5 eccD5 Rv1748 (dark) — hypothetical protein Rv1748 Rv1364c (family_assigned) — sigma factor regulatory protein Rv1364c Rv2598 (family_assigned) — DUF2617 family protein Rv2598 ptrp (family_assigned) — hypothetical protein ptrp cpnT (requalified) — outer membrane channel protein/necrotizing toxin g cpnT Rv1775 (family_assigned) — hypothetical protein Rv1775 mce3R (family_assigned) — TetR family transcriptional regulator Mce3R mce3R Rv1937 (requalified) — FAD-binding oxidoreductase Rv1937 rpsS (requalified) — 30S ribosomal protein S19 rpsS rpsL (requalified) — 30S ribosomal protein S12 rpsL rpsQ (requalified) — 30S ribosomal protein S17 rpsQ rpsC (requalified) — 30S ribosomal protein S3 rpsC rpsE (requalified) — 30S ribosomal protein S5 rpsE rpsN2 (requalified) — 30S ribosomal protein S14 rpsN2 Rv1005c (requalified) — para-aminobenzoate synthase component I Rv1005c trpE (requalified) — anthranilate synthase component I trpE mbtI (requalified) — salicylate synthase mbtI xerC (requalified) — tyrosine recombinase XerC xerC pks12 (requalified) — type I polyketide synthase pks12 Rv0210 (family_assigned) — hypothetical protein Rv0210 Rv0181c (family_assigned) — pirin family protein Rv0181c Rv3434c (family_assigned) — rhomboid-like protein Rv3434c pup (family_assigned) — ubiquitin-like protein Pup pup prcA (family_assigned) — proteasome subunit alpha prcA prcB (family_assigned) — proteasome subunit beta prcB mpa (requalified) — proteasome ATPase mpa bpa (requalified) — proteasome activator protein Bpa bpa pafA (requalified) — Pup--protein ligase pafA eccC5 (requalified) — ESX-5 type VII secretion system protein EccC5 eccC5 eccB5 (family_assigned) — type VII secretion system ESX-5 subunit EccB5 eccB5 mycP5 (requalified) — type VII secretion system ESX-5 serine protease my mycP5 eccC2 (family_assigned) — type VII secretion system ESX-2 FtsK/SpoIIIE famil eccC2 eccE5 (family_assigned) — type VII secretion system ESX-5 subunit EccE5 eccE5 eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 Rv0219 (dark) — hypothetical protein Rv0219 Rv1354c (requalified) — bifunctional diguanylate cyclase/phosphodiesterase Rv1354c

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.