MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2108 · 46 genes shown · anchor PE22 · open gene page → · ← back to 1 hop

Evidence: Min score 0
PPE36 (family_assigned) — PPE family protein PPE36 PPE36 PPE28 (family_assigned) — PPE family protein PPE28 PPE28 PE22 (family_assigned) — PE family protein PE22 PE22 PE25 (family_assigned) — PE family protein PE25 PE25 Rv0265c (family_assigned) — iron ABC transporter substrate-binding lipoprotein Rv0265c PPE37 (family_assigned) — PPE family protein PPE37 PPE37 oplA (family_assigned) — hydantoinase B/oxoprolinase family protein oplA pyrC (requalified) — dihydroorotase pyrC Rv3412 (dark) — DUF5319 domain-containing protein Rv3412 carA (family_assigned) — glutamine-hydrolyzing carbamoyl-phosphate synthase carA Rv0203 (requalified) — hemophore Rv0203 PE15 (family_assigned) — PE family protein PE15 PE15 mhuD (requalified) — mycobilin-forming heme oxygenase MhuD mhuD lppT (dark) — hypothetical protein lppT Rv1147 (family_assigned) — methyltransferase domain-containing protein Rv1147 adhA (family_assigned) — zinc-binding alcohol dehydrogenase family protein adhA Rv3095 (family_assigned) — helix-turn-helix domain-containing protein Rv3095 PPE29 (family_assigned) — PPE family protein PPE29 PPE29 Rv1116 (dark) — hypothetical protein Rv1116 mazF1 (requalified) — toxin MazF1 mazF1 PPE41 (family_assigned) — PPE family protein PPE41 PPE41 Rv1794 (family_assigned) — ESX secretion-associated protein EspG Rv1794 Rv2434c (requalified) — mechanosensitive ion channel Rv2434c Rv2432c (dark) — hypothetical protein Rv2432c nrtS (requalified) — nitrate/nitrite transporter NrtS nrtS Rv2435c (family_assigned) — adenylate/guanylate cyclase domain-containing prot Rv2435c aac (requalified) — aminoglycoside 2'-N-acetyltransferase aac fecB (family_assigned) — iron-siderophore ABC transporter substrate-binding fecB Rv0264c (family_assigned) — allophanate hydrolase subunit 1 Rv0264c Rv0263c (family_assigned) — 5-oxoprolinase/urea amidolyase family protein Rv0263c Rv1289 (family_assigned) — hypothetical protein Rv1289 Rv3839 (requalified) — DUF2470 domain-containing protein Rv3839 mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA hisE (requalified) — phosphoribosyl-ATP pyrophosphatase hisE hisG (requalified) — ATP phosphoribosyltransferase hisG Rv2120c (family_assigned) — glycine zipper 2TM domain-containing protein Rv2120c irtA (family_assigned) — iron ABC transporter ATP-binding protein/permease irtA ggtB (family_assigned) — gamma-glutamyltransferase family protein ggtB ggtA (requalified) — bifunctional cephalosporin acylase/gamma-glutamylt ggtA gshA (requalified) — ergothioneine biosynthesis glutamate--cysteine lig gshA Rv0433 (requalified) — glutamate--cysteine ligase Rv0433 gdh (requalified) — NAD-glutamate dehydrogenase gdh pyrB (family_assigned) — aspartate carbamoyltransferase catalytic subunit pyrB carB (family_assigned) — carbamoyl-phosphate synthase large subunit carB pyrR (family_assigned) — bifunctional pyr operon transcriptional regulator/ pyrR Rv1382 (requalified) — transporter Rv1382

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.