Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2071c · 36 genes shown · anchor cobIJ · open gene page → · ← back to 1 hop

Evidence: Min score 0
cobM (requalified) — precorrin-4 C(11)-methyltransferase cobM cobIJ (requalified) — precorrin-2 C(20)-methyltransferase cobIJ cobL (requalified) — bifunctional cobalt-precorrin-7 (C(5))-methyltrans cobL cobK (requalified) — cobalt-precorrin-6A reductase cobK cobH (requalified) — precorrin-8X methylmutase cobH cobQ1 (requalified) — cobyric acid synthase cobQ1 cobB (requalified) — cobyrinate a%2Cc-diamide synthase cobB Rv2073c (family_assigned) — SDR family NAD(P)-dependent oxidoreductase Rv2073c cobD (requalified) — cobalamin biosynthesis protein cobD cobS (requalified) — adenosylcobinamide-GDP ribazoletransferase cobS Rv2074 (requalified) — F420-dependent biliverdin reductase Rv2074 hemC (requalified) — hydroxymethylbilane synthase hemC Rv2423 (requalified) — class I SAM-dependent methyltransferase Rv2423 cobG (requalified) — precorrin-3B synthase cobG cobN (family_assigned) — cobaltochelatase subunit CobN cobN cobU (requalified) — bifunctional adenosylcobinamide kinase/adenosylcob cobU cobO (requalified) — cob(I)alamin adenosyltransferase cobO cobC (requalified) — aminotransferase cobC ubiA (requalified) — decaprenyl-phosphate phosphoribosyltransferase ubiA dprE1 (requalified) — decaprenylphospho-beta-D-ribofuranose 2-dehydrogen dprE1 Rv1314c (requalified) — cob(I)yrinic acid a%2Cc-diamide adenosyltransferas Rv1314c cobT (requalified) — nicotinate-nucleotide--dimethylbenzimidazole phosp cobT Rv2228c (requalified) — multifunctional RNASE H/alpha-ribazole phosphatase Rv2228c Rv2216 (family_assigned) — TIGR01777 family oxidoreductase Rv2216 Rv1156 (requalified) — HhH-GPD-type base excision DNA repair protein Rv1156 hemD (requalified) — uroporphyrin-III C-methyltransferase hemD hemB (requalified) — porphobilinogen synthase hemB hemA (requalified) — glutamyl-tRNA reductase hemA cysG (requalified) — uroporphyrinogen-III C-methyltransferase cysG hemE (requalified) — uroporphyrinogen decarboxylase hemE Rv0260c (requalified) — uroporphyrinogen-III synthase Rv0260c Rv2067c (requalified) — class I SAM-dependent methyltransferase Rv2067c Rv3899c (family_assigned) — hypothetical protein Rv3899c Rv3435c (family_assigned) — DUF4436 domain-containing protein Rv3435c Rv3166c (family_assigned) — DUF4129 domain-containing protein Rv3166c Rv2079 (family_assigned) — alpha/beta hydrolase Rv2079

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.