MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2066 · 35 genes shown · anchor cobM · open gene page → · ← back to 1 hop

Evidence: Min score 0
cobIJ (requalified) — precorrin-2 C(20)-methyltransferase cobIJ cobM (requalified) — precorrin-4 C(11)-methyltransferase cobM cobH (requalified) — precorrin-8X methylmutase cobH cobK (requalified) — cobalt-precorrin-6A reductase cobK cobL (requalified) — bifunctional cobalt-precorrin-7 (C(5))-methyltrans cobL cobQ1 (requalified) — cobyric acid synthase cobQ1 cobG (requalified) — precorrin-3B synthase cobG cobS (requalified) — adenosylcobinamide-GDP ribazoletransferase cobS cysG (requalified) — uroporphyrinogen-III C-methyltransferase cysG hemD (requalified) — uroporphyrin-III C-methyltransferase hemD Rv2423 (requalified) — class I SAM-dependent methyltransferase Rv2423 cobN (family_assigned) — cobaltochelatase subunit CobN cobN cobB (requalified) — cobyrinate a%2Cc-diamide synthase cobB Rv2073c (family_assigned) — SDR family NAD(P)-dependent oxidoreductase Rv2073c cobU (requalified) — bifunctional adenosylcobinamide kinase/adenosylcob cobU cobD (requalified) — cobalamin biosynthesis protein cobD cobO (requalified) — cob(I)alamin adenosyltransferase cobO cysC (requalified) — adenylyl-sulfate kinase cysC mazF7 (requalified) — mRNA interferase MazF7 mazF7 cobT (requalified) — nicotinate-nucleotide--dimethylbenzimidazole phosp cobT Rv2228c (requalified) — multifunctional RNASE H/alpha-ribazole phosphatase Rv2228c Rv1314c (requalified) — cob(I)yrinic acid a%2Cc-diamide adenosyltransferas Rv1314c hemC (requalified) — hydroxymethylbilane synthase hemC Rv0260c (requalified) — uroporphyrinogen-III synthase Rv0260c Rv0259c (family_assigned) — sirohydrochlorin chelatase Rv0259c hemB (requalified) — porphobilinogen synthase hemB hemA (requalified) — glutamyl-tRNA reductase hemA Rv0514 (dark) — hypothetical protein Rv0514 Rv2067c (requalified) — class I SAM-dependent methyltransferase Rv2067c Rv3899c (family_assigned) — hypothetical protein Rv3899c Rv3435c (family_assigned) — DUF4436 domain-containing protein Rv3435c Rv3166c (family_assigned) — DUF4129 domain-containing protein Rv3166c Rv2079 (family_assigned) — alpha/beta hydrolase Rv2079 Rv2850c (family_assigned) — magnesium chelatase subunit D family protein Rv2850c cobC (requalified) — aminotransferase cobC

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.