MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2061c · 46 genes shown · anchor cobN · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv2061c (requalified) — PPOX class F420-dependent oxidoreductase Rv2061c cobN (family_assigned) — cobaltochelatase subunit CobN cobN Rv1558 (requalified) — F420H(2)-dependent quinone reductase Rv1558 Rv0044c (requalified) — LLM class F420-dependent oxidoreductase Rv0044c cobIJ (requalified) — precorrin-2 C(20)-methyltransferase cobIJ cobG (requalified) — precorrin-3B synthase cobG cobH (requalified) — precorrin-8X methylmutase cobH fgd1 (requalified) — glucose-6-phosphate dehydrogenase (coenzyme-F420) fgd1 moaD2 (family_assigned) — molybdopterin synthase subunit MoaD2 moaD2 mazE7 (requalified) — antitoxin MazE7 mazE7 mazF7 (requalified) — mRNA interferase MazF7 mazF7 Rv3196 (family_assigned) — hypothetical protein Rv3196 Rv2609c (family_assigned) — NUDIX domain-containing protein Rv2609c cobO (requalified) — cob(I)alamin adenosyltransferase cobO cobB (requalified) — cobyrinate a%2Cc-diamide synthase cobB cobL (requalified) — bifunctional cobalt-precorrin-7 (C(5))-methyltrans cobL Rv2850c (family_assigned) — magnesium chelatase subunit D family protein Rv2850c Rv1314c (requalified) — cob(I)yrinic acid a%2Cc-diamide adenosyltransferas Rv1314c mmpL6 (requalified) — transmembrane transport protein MmpL6 mmpL6 ilvA (requalified) — threonine ammonia-lyase ilvA fbiA (requalified) — 2-phospho-L-lactate transferase fbiA Rv3520c (requalified) — coenzyme F420-dependent oxidoreductase Rv3520c Rv0045c (family_assigned) — alpha/beta hydrolase Rv0045c ino1 (requalified) — inositol-3-phosphate synthase ino1 Rv0043c (family_assigned) — GntR family transcriptional regulator Rv0043c fgd2 (requalified) — F420-dependent hydroxymycolic acid dehydrogenase fgd2 ddn (requalified) — deazaflavin-dependent nitroreductase Ddn ddn cobM (requalified) — precorrin-4 C(11)-methyltransferase cobM cobK (requalified) — cobalt-precorrin-6A reductase cobK cobQ1 (requalified) — cobyric acid synthase cobQ1 cysC (requalified) — adenylyl-sulfate kinase cysC cysG (requalified) — uroporphyrinogen-III C-methyltransferase cysG pta (requalified) — phosphate acetyltransferase pta ackA (requalified) — acetate kinase ackA Rv0406c (family_assigned) — beta lactamase-like protein Rv0406c moaE2 (family_assigned) — molybdopterin synthase subunit MoaE2 moaE2 moaX (requalified) — MoaD-MoaE fusion protein MoaX moaX moaE1 (family_assigned) — molybdopterin synthase catalytic subunit 1 moaE1 moaA2 (requalified) — GTP 3'%2C8-cyclase MoaA moaA2 moeB1 (requalified) — adenylyltransferase/sulfurtransferase MoeZ moeB1 moeB2 (requalified) — molybdenum cofactor biosynthesis protein MoeB moeB2 mazF9 (requalified) — type II toxin-antitoxin system toxin endoribonucle mazF9 mazF1 (requalified) — toxin MazF1 mazF1 mazE9 (requalified) — antitoxin MazE9 mazE9 Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c Rv3195 (requalified) — zinc-dependent metalloprotease Rv3195

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.