MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2048c · 40 genes shown · anchor fas · open gene page → · ← back to 1 hop

Evidence: Min score 0
pks12 (requalified) — type I polyketide synthase pks12 fas (requalified) — fatty acid synthase fas fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD mbtB (requalified) — phenyloxazoline synthase MbtB mbtB ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC mas (requalified) — mycocerosate synthase mas pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 nuoC (family_assigned) — NADH-quinone oxidoreductase subunit C nuoC nuoI (family_assigned) — NADH-quinone oxidoreductase subunit NuoI nuoI nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp nuoB (family_assigned) — NADH-quinone oxidoreductase subunit B nuoB pks1 (requalified) — polyketide synthase pks1 pks7 (requalified) — type I polyketide synthase pks7 pks17 (requalified) — polyketide synthase pks17 accD3 (family_assigned) — carboxyl transferase domain-containing protein accD3 pks6 (requalified) — membrane bound polyketide synthase pks6 kasA (requalified) — 3-oxoacyl-ACP synthase KasA kasA kasB (requalified) — 3-oxoacyl-ACP synthase 2 kasB mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA pks13 (requalified) — polyketide synthase Pks13 pks13 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtE (requalified) — peptide synthetase mbtE mbtC (requalified) — polyketide synthetase MbtC mbtC ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB papA1 (requalified) — acyltransferase PapA1 papA1 nuoF (family_assigned) — NADH-quinone oxidoreductase subunit NuoF nuoF nuoD (family_assigned) — NADH dehydrogenase (quinone) subunit D nuoD nuoA (family_assigned) — NADH-quinone oxidoreductase subunit A nuoA nuoM (family_assigned) — NADH-quinone oxidoreductase subunit M nuoM nuoE (family_assigned) — NADH-quinone oxidoreductase subunit NuoE nuoE nuoN (family_assigned) — NADH-quinone oxidoreductase subunit NuoN nuoN nuoJ (family_assigned) — NADH-quinone oxidoreductase subunit J nuoJ nuoG (family_assigned) — NADH-quinone oxidoreductase subunit G nuoG nuoH (family_assigned) — NADH-quinone oxidoreductase subunit NuoH nuoH fadD10 (requalified) — fatty-acid--CoA ligase FadD10 fadD10 nuoK (family_assigned) — NADH-quinone oxidoreductase subunit NuoK nuoK pks15 (requalified) — polyketide synthase pks15

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.