Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2022c · 45 genes shown · anchor higA2 · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv2022c (family_assigned) — type II toxin-antitoxin system RelE/ParE family to Rv2022c Rv2021c (family_assigned) — XRE family transcriptional regulator Rv2021c Rv3183 (family_assigned) — XRE family transcriptional regulator Rv3183 Rv2023c (dark) — hypothetical protein Rv2023c Rv2020c (family_assigned) — Conserved hypothetical protein Rv2020c higA (requalified) — type II toxin-antitoxin system antitoxin HigA higA vapC46 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC46 Rv3750c (requalified) — excisionase Rv3750c relG (family_assigned) — type II toxin-antitoxin system RelE/ParE family to relG relF (requalified) — type II toxin-antitoxin system antitoxin RelF relF Rv0918 (family_assigned) — DUF1778 domain-containing protein Rv0918 Rv3749c (family_assigned) — hypothetical protein Rv3749c vapC1 (requalified) — type II toxin-antitoxin system ribonuclease VapC1 vapC1 Rv3182 (family_assigned) — type II toxin-antitoxin system RelE/ParE family to Rv3182 Rv0744c (family_assigned) — helix-turn-helix domain-containing protein Rv0744c Rv0332 (family_assigned) — hypothetical protein Rv0332 mftR (family_assigned) — mycofactocin system transcriptional regulator mftR Rv3263 (requalified) — class I SAM-dependent methyltransferase Rv3263 Rv3066 (family_assigned) — TetR/AcrR family transcriptional regulator Rv3066 Rv3840 (family_assigned) — transcriptional regulator Rv3840 Rv1776c (family_assigned) — TetR/AcrR family transcriptional regulator Rv1776c Rv2024c (family_assigned) — hypothetical protein Rv2024c ogt (requalified) — methylated-DNA--protein-cysteine methyltransferase ogt esxS (requalified) — ESAT-6 like protein EsxS esxS Rv1957 (requalified) — SecB-like chaperone Rv1957 higB (requalified) — type II toxin-antitoxin system toxin HigB higB PPE55 (family_assigned) — PPE family protein PPE55 PPE55 PPE56 (family_assigned) — PPE family protein PPE56 PPE56 PPE8 (family_assigned) — PPE family protein PPE8 PPE8 Rv0836c (family_assigned) — hypothetical protein Rv0836c vapB46 (requalified) — antitoxin VapB46 vapB46 vapB47 (requalified) — antitoxin VapB47 vapB47 vapC12 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC12 vapB5 (family_assigned) — type II toxin-antitoxin system Phd/YefM family ant vapB5 vapC9 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC9 vapC5 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC5 Rv2018 (family_assigned) — DUF433 domain-containing protein Rv2018 relE (requalified) — type II toxin-antitoxin system mRNA interferase Re relE relB (family_assigned) — type II toxin-antitoxin system Phd/YefM family ant relB mazF2 (family_assigned) — type II toxin-antitoxin system PemK/MazF family to mazF2 mazF5 (family_assigned) — type II toxin-antitoxin system PemK/MazF family to mazF5 Rv2864c (family_assigned) — penicillin-binding protein Rv2864c relJ (requalified) — type II toxin-antitoxin system antitoxin RelJ relJ relK (family_assigned) — Txe/YoeB family addiction module toxin relK Rv0919 (family_assigned) — GNAT family N-acetyltransferase Rv0919

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.