MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2020c · 36 genes shown · anchor higA2 · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv2020c (family_assigned) — Conserved hypothetical protein Rv2020c Rv2024c (family_assigned) — hypothetical protein Rv2024c Rv2022c (family_assigned) — type II toxin-antitoxin system RelE/ParE family to Rv2022c Rv2021c (family_assigned) — XRE family transcriptional regulator Rv2021c Rv2023c (dark) — hypothetical protein Rv2023c ogt (requalified) — methylated-DNA--protein-cysteine methyltransferase ogt esxS (requalified) — ESAT-6 like protein EsxS esxS PE_PGRS22 (family_assigned) — PE-PGRS family protein PE_PGRS22 PE_PGRS22 hsdM (requalified) — class I SAM-dependent DNA methyltransferase hsdM Rv3263 (requalified) — class I SAM-dependent methyltransferase Rv3263 Rv2119 (family_assigned) — RecB family exonuclease Rv2119 hsdS (family_assigned) — restriction endonuclease subunit S hsdS treS (requalified) — maltose alpha-D-glucosyltransferase treS Rv3183 (family_assigned) — XRE family transcriptional regulator Rv3183 higA (requalified) — type II toxin-antitoxin system antitoxin HigA higA vapC46 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC46 Rv3182 (family_assigned) — type II toxin-antitoxin system RelE/ParE family to Rv3182 Rv0744c (family_assigned) — helix-turn-helix domain-containing protein Rv0744c Rv0332 (family_assigned) — hypothetical protein Rv0332 alkA (family_assigned) — bifunctional regulatory protein/DNA repair enzyme alkA Rv1318c (family_assigned) — adenylate/guanylate cyclase domain-containing prot Rv1318c tagA (requalified) — DNA-3-methyladenine glycosylase I tagA Rv1321 (requalified) — endonuclease NucS Rv1321 Rv1322 (family_assigned) — hypothetical protein Rv1322 Rv1319c (requalified) — adenylate cyclase Rv1319c esxR (family_assigned) — WXG100 family type VII secretion target esxR esxQ (requalified) — type VII secretion system ESX-3 effector EsxQ esxQ esxH (requalified) — type VII secretion system effector EsxH esxH PPE46 (family_assigned) — PPE family protein PPE46 PPE46 esxV (requalified) — ESAT-6 like protein EsxV esxV esxB (family_assigned) — type VII secretion system ESX-1 WXG100 family targ esxB zmp1 (requalified) — zinc metalloprotease Zmp1 zmp1 Rv1146 (requalified) — transmembrane transport protein Rv1146 PPE13 (family_assigned) — PPE family protein PPE13 PPE13 PPE9 (family_assigned) — PPE family protein PPE9 PPE9 PPE5 (family_assigned) — PPE family protein PPE5 PPE5

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.