MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1998c · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv1998c (family_assigned) — isocitrate lyase/phosphoenolpyruvate mutase family Rv1998c Rv3195 (requalified) — zinc-dependent metalloprotease Rv3195 mshD (requalified) — mycothiol synthase mshD prpD (requalified) — 2-methylcitrate dehydratase prpD ilvB2 (family_assigned) — thiamine pyrophosphate-binding protein ilvB2 gltA2 (requalified) — citrate synthase gltA2 prpC (requalified) — 2-methylcitrate synthase prpC citA (requalified) — citrate synthase 2 citA Rv1999c (family_assigned) — APC family permease Rv1999c alkA (family_assigned) — bifunctional regulatory protein/DNA repair enzyme alkA glcB (requalified) — malate synthase G glcB acs (requalified) — acetate--CoA ligase acs mdh (requalified) — malate dehydrogenase mdh Rv3194c (family_assigned) — PDZ domain-containing protein Rv3194c Rv3196 (family_assigned) — hypothetical protein Rv3196 clpP2 (family_assigned) — ATP-dependent CLP protease proteolytic subunit Clp clpP2 Rv1830 (family_assigned) — HTH-type transcriptional regulator Rv1830 Rv2413c (family_assigned) — DNA polymerase III subunit delta Rv2413c Rv0818 (requalified) — response regulator transcription factor Rv0818 ppk1 (requalified) — RNA degradosome polyphosphate kinase ppk1 Rv2466c (family_assigned) — Rv2466c family mycothiol-dependent reductase Rv2466c mshC (requalified) — cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D mshC mca (requalified) — mycothiol conjugate amidase Mca mca Rv1129c (family_assigned) — short-chain fatty acyl-CoA regulator family protei Rv1129c Rv1132 (family_assigned) — DUF3556 domain-containing protein Rv1132 ramB (family_assigned) — acetate metabolism transcriptional regulator RamB ramB ilvN (family_assigned) — acetolactate synthase small subunit ilvN ilvC (requalified) — ketol-acid reductoisomerase ilvC leuB (requalified) — 3-isopropylmalate dehydrogenase leuB ilvA (requalified) — threonine ammonia-lyase ilvA ilvB1 (family_assigned) — acetolactate synthase large subunit IlvB ilvB1 ilvG (requalified) — acetolactate synthase ilvG acn (requalified) — iron-regulated aconitate hydratase Acn acn bkdC (family_assigned) — dihydrolipoamide acetyltransferase family protein bkdC Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c Rv0650 (family_assigned) — ROK family protein Rv0650 Rv0218 (requalified) — molybdopterin-dependent oxidoreductase Rv0218 glgE (requalified) — alpha-1,4-glucan:maltose-1-phosphate maltosyltrans glgE aglA (family_assigned) — glycoside hydrolase family 13 protein aglA treS (requalified) — maltose alpha-D-glucosyltransferase treS Rv0648 (requalified) — alpha-mannosidase Rv0648 ogt (requalified) — methylated-DNA--protein-cysteine methyltransferase ogt Rv1318c (family_assigned) — adenylate/guanylate cyclase domain-containing prot Rv1318c xthA (requalified) — exodeoxyribonuclease III protein XthA xthA Rv1321 (requalified) — endonuclease NucS Rv1321 Rv1322 (family_assigned) — hypothetical protein Rv1322

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.