MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1990c · 45 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv1990c (family_assigned) — antitoxin Xre/MbcA/ParS toxin-binding domain-conta Rv1990c Rv1989c (family_assigned) — RES family NAD+ phosphorylase Rv1989c Rv2034 (family_assigned) — metalloregulator ArsR/SmtB family transcription fa Rv2034 Rv2021c (family_assigned) — XRE family transcriptional regulator Rv2021c mftR (family_assigned) — mycofactocin system transcriptional regulator mftR Rv0238 (family_assigned) — TetR/AcrR family transcriptional regulator Rv0238 whiA (family_assigned) — DNA-binding protein WhiA whiA Rv0023 (family_assigned) — helix-turn-helix transcriptional regulator Rv0023 vapB23 (requalified) — antitoxin VapB23 vapB23 Rv3188 (family_assigned) — antitoxin Xre/MbcA/ParS toxin-binding domain-conta Rv3188 pncB1 (requalified) — nicotinate phosphoribosyltransferase pncB1 Rv3189 (family_assigned) — RES family NAD+ phosphorylase Rv3189 Rv2035 (family_assigned) — SRPBCC family protein Rv2035 Rv2036 (family_assigned) — maleylpyruvate isomerase family mycothiol-dependen Rv2036 sigI (requalified) — RNA polymerase sigma factor SigI sigI sigJ (family_assigned) — sigma-70 family RNA polymerase sigma factor SigJ sigJ Rv2033c (family_assigned) — DUF3097 domain-containing protein Rv2033c cmtR (family_assigned) — Cd(II)/Pb(II)-sensing metalloregulatory transcript cmtR Rv2022c (family_assigned) — type II toxin-antitoxin system RelE/ParE family to Rv2022c Rv3182 (family_assigned) — type II toxin-antitoxin system RelE/ParE family to Rv3182 Rv2023c (dark) — hypothetical protein Rv2023c Rv0744c (family_assigned) — helix-turn-helix domain-containing protein Rv0744c Rv2020c (family_assigned) — Conserved hypothetical protein Rv2020c Rv0332 (family_assigned) — hypothetical protein Rv0332 Rv3830c (family_assigned) — TetR/AcrR family transcriptional regulator Rv3830c mftB (requalified) — mycofactocin biosynthesis chaperone MftB mftB mftC (requalified) — mycofactocin radical SAM maturase mftC Rv3183 (family_assigned) — XRE family transcriptional regulator Rv3183 Rv0690c (family_assigned) — DUF2332 domain-containing protein Rv0690c Rv3167c (family_assigned) — TetR/AcrR family transcriptional regulator Rv3167c lpqI (requalified) — lipoprotein LpqI lpqI vapB24 (requalified) — antitoxin vapB24 vapC24 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC24 Rv0158 (family_assigned) — TetR/AcrR family transcriptional regulator Rv0158 Rv1534 (family_assigned) — TetR family transcriptional regulator Rv1534 Rv0236A (dark) — hypothetical protein Rv0236A cuvA (requalified) — carbon utilization/virulence protein CuvA cuvA rapZ (requalified) — RNase adapter RapZ rapZ uvrC (family_assigned) — excinuclease ABC subunit UvrC uvrC xerC (requalified) — tyrosine recombinase XerC xerC Rv2699c (dark) — DUF4193 domain-containing protein Rv2699c rbpA (family_assigned) — RNA polymerase-binding protein RbpA rbpA Rv0025 (dark) — DUF4226 domain-containing protein Rv0025 Rv0024 (family_assigned) — C40 family peptidase Rv0024 whiB5 (family_assigned) — transcriptional regulator WhiB5 whiB5

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.