Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1989c · 43 genes shown · anchor mbcA · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv1989c (family_assigned) — RES family NAD+ phosphorylase Rv1989c Rv1990c (family_assigned) — antitoxin Xre/MbcA/ParS toxin-binding domain-conta Rv1990c Rv3188 (family_assigned) — antitoxin Xre/MbcA/ParS toxin-binding domain-conta Rv3188 Rv2034 (family_assigned) — metalloregulator ArsR/SmtB family transcription fa Rv2034 pncB1 (requalified) — nicotinate phosphoribosyltransferase pncB1 Rv3189 (family_assigned) — RES family NAD+ phosphorylase Rv3189 Rv2035 (family_assigned) — SRPBCC family protein Rv2035 Rv1985c (family_assigned) — ArgP/LysG family DNA-binding transcriptional regul Rv1985c Rv0837c (family_assigned) — type IV toxin-antitoxin system AbiEi family antito Rv0837c Rv0918 (family_assigned) — DUF1778 domain-containing protein Rv0918 nrdF1 (family_assigned) — ribonucleoside-diphosphate reductase subunit beta nrdF1 Rv3698 (family_assigned) — hypothetical protein Rv3698 Rv2021c (family_assigned) — XRE family transcriptional regulator Rv2021c mftR (family_assigned) — mycofactocin system transcriptional regulator mftR Rv0238 (family_assigned) — TetR/AcrR family transcriptional regulator Rv0238 Rv2022c (family_assigned) — type II toxin-antitoxin system RelE/ParE family to Rv2022c Rv2036 (family_assigned) — maleylpyruvate isomerase family mycothiol-dependen Rv2036 sigI (requalified) — RNA polymerase sigma factor SigI sigI sigJ (family_assigned) — sigma-70 family RNA polymerase sigma factor SigJ sigJ Rv2033c (family_assigned) — DUF3097 domain-containing protein Rv2033c cmtR (family_assigned) — Cd(II)/Pb(II)-sensing metalloregulatory transcript cmtR pncA (requalified) — pyrazinamidase PncA pncA nadC (requalified) — carboxylating nicotinate-nucleotide diphosphorylas nadC pncB2 (requalified) — nicotinate phosphoribosyltransferase pncB2 cinA (requalified) — competence/damage-inducible protein A cinA nadR (requalified) — nicotinamide-nucleotide adenylyltransferase nadR nadD (requalified) — nicotinate-nucleotide adenylyltransferase nadD Rv3351c (family_assigned) — hypothetical protein Rv3351c Rv3071 (family_assigned) — DUF190 domain-containing protein Rv3071 Rv3295 (family_assigned) — TetR/AcrR family transcriptional regulator Rv3295 lysE (requalified) — L-lysine exporter lysE Rv3736 (family_assigned) — AraC family transcriptional regulator Rv3736 Rv3167c (family_assigned) — TetR/AcrR family transcriptional regulator Rv3167c Rv3183 (family_assigned) — XRE family transcriptional regulator Rv3183 Rv3263 (requalified) — class I SAM-dependent methyltransferase Rv3263 Rv0836c (family_assigned) — hypothetical protein Rv0836c PPE8 (family_assigned) — PPE family protein PPE8 PPE8 PE_PGRS28 (family_assigned) — PE-PGRS family protein PE_PGRS28 PE_PGRS28 PE_PGRS43 (family_assigned) — PE-PGRS family protein PE_PGRS43 PE_PGRS43 PPE55 (family_assigned) — PPE family protein PPE55 PPE55 Rv1004c (family_assigned) — hypothetical protein Rv1004c Rv0919 (family_assigned) — GNAT family N-acetyltransferase Rv0919 vapC24 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC24

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.