MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1978 · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv1978 (requalified) — class I SAM-dependent methyltransferase Rv1978 Rv2687c (family_assigned) — fluoroquinolone transporter permease Rv2687c Rv2686c (family_assigned) — fluoroquinolones efflux ABC transporter permease Rv2686c rsmA (requalified) — anti-sigma-M factor RsmA rsmA Rv0210 (family_assigned) — hypothetical protein Rv0210 pks4 (requalified) — polyketide beta-ketoacyl synthase pks4 Rv3604c (dark) — DUF6779 domain-containing protein Rv3604c Rv2633c (requalified) — non-heme di-iron catalase Rv2633c Rv0955 (family_assigned) — DUF6350 family protein Rv0955 Rv3896c (requalified) — transglycosylase Rv3896c Rv0804 (family_assigned) — CPBP family intramembrane glutamic endopeptidase Rv0804 Rv3786c (family_assigned) — peptidoglycan DD-metalloendopeptidase family prote Rv3786c Rv1733c (family_assigned) — hypothetical protein Rv1733c Rv2688c (family_assigned) — ABC transporter ATP-binding protein Rv2688c sigM (requalified) — ECF RNA polymerase sigma factor SigM sigM Rv3909 (dark) — hypothetical protein Rv3909 murJ (requalified) — murein biosynthesis integral membrane protein MurJ murJ mutT4 (requalified) — NUDIX hydrolase mutT4 trxC (requalified) — thioredoxin trxC trxB2 (requalified) — thioredoxin-disulfide reductase trxB2 Rv0209 (family_assigned) — hypothetical protein Rv0209 trmB (requalified) — tRNA (guanosine(46)-N7)-methyltransferase TrmB trmB Rv0207c (family_assigned) — NYN domain-containing protein Rv0207c Rv2474c (family_assigned) — hypothetical protein Rv2474c rsdA (requalified) — anti-sigma D factor RsdA rsdA fas (requalified) — fatty acid synthase fas pks3 (requalified) — polyketide beta-ketoacyl synthase pks3 papA3 (requalified) — acyltransferase PapA3 papA3 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 mbtB (requalified) — phenyloxazoline synthase MbtB mbtB Rv3605c (family_assigned) — DUF3180 domain-containing protein Rv3605c pimE (requalified) — mannosyltransferase pimE PPE2 (family_assigned) — PPE family protein PPE2 PPE2 Rv2632c (family_assigned) — DUF1876 domain-containing protein Rv2632c Rv0688 (requalified) — FAD/NAD(P)-binding oxidoreductase Rv0688 Rv1869c (requalified) — FAD-dependent oxidoreductase Rv1869c Rv0954 (requalified) — DUF5336 domain-containing protein Rv0954 mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG purN (requalified) — phosphoribosylglycinamide formyltransferase purN purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH eccC2 (family_assigned) — type VII secretion system ESX-2 FtsK/SpoIIIE famil eccC2 eccB2 (family_assigned) — type VII secretion system ESX-2 subunit EccB2 eccB2 purL (family_assigned) — phosphoribosylformylglycinamidine synthase subunit purL Rv3787c (requalified) — class I SAM-dependent methyltransferase Rv3787c Rv2812 (family_assigned) — helix-turn-helix domain-containing protein Rv2812

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.