MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1977 · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv1977 (family_assigned) — M48 family metallopeptidase Rv1977 iniA (requalified) — isoniazid inductible protein IniA iniA Rv1978 (requalified) — class I SAM-dependent methyltransferase Rv1978 ftsH (requalified) — ATP-dependent zinc metalloprotease FtsH ftsH Rv0966c (dark) — DUF1707 domain-containing protein Rv0966c grpE (requalified) — nucleotide exchange factor GrpE grpE cysC (requalified) — adenylyl-sulfate kinase cysC clpB (requalified) — chaperone protein ClpB clpB ephA (requalified) — epoxide hydrolase EphA ephA Rv1979c (family_assigned) — APC family permease Rv1979c rip (requalified) — zinc metalloprotease Rip rip Rv1976c (family_assigned) — NYN domain-containing protein Rv1976c pepN (requalified) — aminopeptidase PepN pepN iniC (requalified) — isoniazid-induced dynamin-like GTPase IniC iniC iniB (requalified) — isoniazid-induced protein IniB iniB iniR (family_assigned) — isoniazid response ATPase/transcriptional regulato iniR Rv0312 (family_assigned) — Hsp70 family protein Rv0312 Rv2264c (family_assigned) — Hsp70 family protein Rv2264c Rv3835 (family_assigned) — septum formation family protein Rv3835 Rv2687c (family_assigned) — fluoroquinolone transporter permease Rv2687c Rv2686c (family_assigned) — fluoroquinolones efflux ABC transporter permease Rv2686c rsmA (requalified) — anti-sigma-M factor RsmA rsmA Rv0210 (family_assigned) — hypothetical protein Rv0210 pks4 (requalified) — polyketide beta-ketoacyl synthase pks4 Rv3604c (dark) — DUF6779 domain-containing protein Rv3604c folE (requalified) — GTP cyclohydrolase I FolE folE folB (requalified) — dihydroneopterin aldolase folB Rv1488 (family_assigned) — SPFH domain-containing protein Rv1488 Rv3090 (family_assigned) — SPFH domain-containing protein Rv3090 folP1 (requalified) — dihydropteroate synthase folP1 rplS (requalified) — 50S ribosomal protein L19 rplS Rv0965c (family_assigned) — hypothetical protein Rv0965c csoR (requalified) — copper-sensing transcriptional repressor CsoR csoR ponA2 (requalified) — bifunctional penicillin-insensitive transglycosyla ponA2 dosT (requalified) — two-component system sensor histidine kinase DosT dosT Rv0845 (requalified) — sensor histidine kinase NarS Rv0845 devS (requalified) — two-component system sensor histidine kinase DevS devS dnaK (requalified) — molecular chaperone DnaK dnaK dnaJ1 (requalified) — chaperone protein DnaJ dnaJ1 hspR (family_assigned) — heat shock transcriptional regulator HspR hspR groEL2 (requalified) — chaperonin GroEL groEL2 Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c subI (family_assigned) — sulfate ABC transporter substrate-binding protein subI cysD (family_assigned) — sulfate adenylyltransferase subunit CysD cysD cysT (family_assigned) — sulfate ABC transporter permease subunit CysT cysT cysH (requalified) — phosphoadenylyl-sulfate reductase cysH

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.