MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1957 · 46 genes shown · anchor higA · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv1957 (requalified) — SecB-like chaperone Rv1957 higA (requalified) — type II toxin-antitoxin system antitoxin HigA higA higB (requalified) — type II toxin-antitoxin system toxin HigB higB guaB1 (family_assigned) — GuaB1 family IMP dehydrogenase-related protein guaB1 cbs (requalified) — cystathionine beta-synthase cbs Rv1954A (dark) — Hypothetical protein Rv1954A relE (requalified) — type II toxin-antitoxin system mRNA interferase Re relE Rv1954c (requalified) — hypothetical protein Rv1954c Rv2021c (family_assigned) — XRE family transcriptional regulator Rv2021c Rv2022c (family_assigned) — type II toxin-antitoxin system RelE/ParE family to Rv2022c Rv3182 (family_assigned) — type II toxin-antitoxin system RelE/ParE family to Rv3182 PPE55 (family_assigned) — PPE family protein PPE55 PPE55 PPE56 (family_assigned) — PPE family protein PPE56 PPE56 PPE8 (family_assigned) — PPE family protein PPE8 PPE8 Rv0836c (family_assigned) — hypothetical protein Rv0836c guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA purA (requalified) — adenylosuccinate synthase purA purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH guaB2 (requalified) — IMP dehydrogenase guaB2 rdgB (family_assigned) — RdgB/HAM1 family non-canonical purine NTP pyrophos rdgB guaB3 (family_assigned) — GuaB3 family IMP dehydrogenase-related protein guaB3 metB (requalified) — cystathionine gamma-synthase metB metZ (requalified) — O-succinylhomoserine sulfhydrylase metZ cysE (requalified) — serine O-acetyltransferase cysE sahH (requalified) — adenosylhomocysteinase sahH glyA1 (requalified) — serine hydroxymethyltransferase glyA1 glyA2 (requalified) — serine hydroxymethyltransferase glyA2 rpfE (requalified) — resuscitation-promoting factor protein RpfE rpfE rpfC (requalified) — resuscitation-promoting factor RpfC rpfC rpfD (requalified) — resuscitation-promoting factor protein RpfD rpfD rpfA (requalified) — resuscitation-promoting factor protein RpfA rpfA Rv1861 (family_assigned) — GlsB/YeaQ/YmgE family stress response membrane pro Rv1861 relB (family_assigned) — type II toxin-antitoxin system Phd/YefM family ant relB relF (requalified) — type II toxin-antitoxin system antitoxin RelF relF Rv1245c (family_assigned) — SDR family NAD(P)-dependent oxidoreductase Rv1245c mazF2 (family_assigned) — type II toxin-antitoxin system PemK/MazF family to mazF2 mazF5 (family_assigned) — type II toxin-antitoxin system PemK/MazF family to mazF5 Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c Rv2660c (dark) — hypothetical protein Rv2660c Rv1374c (dark) — hypothetical protein Rv1374c usfY (family_assigned) — hypothetical protein usfY Rv0188 (requalified) — SPW repeat protein Rv0188 Rv2023c (dark) — hypothetical protein Rv2023c Rv0744c (family_assigned) — helix-turn-helix domain-containing protein Rv0744c Rv2020c (family_assigned) — Conserved hypothetical protein Rv2020c Rv0332 (family_assigned) — hypothetical protein Rv0332

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.