MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1842c · 46 genes shown · anchor guaB1 · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv1842c (family_assigned) — hemolysin family protein Rv1842c Rv1841c (family_assigned) — hemolysin family protein Rv1841c guaB1 (family_assigned) — GuaB1 family IMP dehydrogenase-related protein guaB1 gnd1 (requalified) — 6-phosphogluconate dehydrogenase gnd1 blaR (family_assigned) — M56 family metallopeptidase blaR blaI (requalified) — transcriptional repressor BlaI blaI glcB (requalified) — malate synthase G glcB Rv1836c (family_assigned) — substrate-binding domain-containing protein Rv1836c PE_PGRS34 (family_assigned) — PE-PGRS family protein PE_PGRS34 PE_PGRS34 dnaJ2 (requalified) — molecular chaperone DnaJ dnaJ2 Rv2367c (requalified) — endoribonuclease Rv2367c guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA purA (requalified) — adenylosuccinate synthase purA purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH guaB2 (requalified) — IMP dehydrogenase guaB2 rdgB (family_assigned) — RdgB/HAM1 family non-canonical purine NTP pyrophos rdgB guaB3 (family_assigned) — GuaB3 family IMP dehydrogenase-related protein guaB3 devB (requalified) — 6-phosphogluconolactonase devB zwf1 (requalified) — glucose-6-phosphate 1-dehydrogenase zwf1 rpe (requalified) — ribulose-phosphate 3-epimerase rpe zwf2 (requalified) — glucose-6-phosphate dehydrogenase zwf2 gnd2 (requalified) — decarboxylating 6-phosphogluconate dehydrogenase gnd2 rpiB (requalified) — ribose-5-phosphate isomerase B rpiB iniA (requalified) — isoniazid inductible protein IniA iniA Rv1847 (family_assigned) — PaaI family thioesterase Rv1847 icl1 (requalified) — isocitrate lyase icl1 aceAa (requalified) — isocitrate lyase AceAa aceAa aceAb (requalified) — isocitrate lyase AceAb aceAb acs (requalified) — acetate--CoA ligase acs pta (requalified) — phosphate acetyltransferase pta gltA2 (requalified) — citrate synthase gltA2 Rv1835c (family_assigned) — CocE/NonD family hydrolase Rv1835c Rv1324 (requalified) — co-chaperone YbbN Rv1324 ubiA (requalified) — decaprenyl-phosphate phosphoribosyltransferase ubiA Rv1125 (family_assigned) — WS/DGAT domain-containing protein Rv1125 pirG (requalified) — exported repetitive protein pirG rplU (requalified) — 50S ribosomal protein L21 rplU rpsT (requalified) — 30S ribosomal protein S20 rpsT rplM (requalified) — 50S ribosomal protein L13 rplM rpmI (requalified) — 50S ribosomal protein L35 rpmI rpsP (requalified) — 30S ribosomal protein S16 rpsP rpmF (requalified) — 50S ribosomal protein L32 rpmF dnaK (requalified) — molecular chaperone DnaK dnaK Rv2372c (requalified) — 16S rRNA (uracil(1498)-N(3))-methyltransferase Rv2372c htpG (requalified) — molecular chaperone HtpG htpG Rv2264c (family_assigned) — Hsp70 family protein Rv2264c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.