MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1816 · 46 genes shown · anchor eccD2 · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv1816 (family_assigned) — HTH-type transcriptional regulator Rv1816 Rv1815 (family_assigned) — hypothetical protein Rv1815 Rv2423 (requalified) — class I SAM-dependent methyltransferase Rv2423 Rv3899c (family_assigned) — hypothetical protein Rv3899c Rv2067c (requalified) — class I SAM-dependent methyltransferase Rv2067c eccD2 (family_assigned) — type VII secretion system ESX-2 subunit EccD2 eccD2 Rv1817 (family_assigned) — FAD-binding protein Rv1817 rslA (requalified) — anti-sigma-L factor RslA rslA Rv3435c (family_assigned) — DUF4436 domain-containing protein Rv3435c Rv1748 (dark) — hypothetical protein Rv1748 erg3 (requalified) — membrane-bound C-5 sterol desaturase erg3 pth (requalified) — aminoacyl-tRNA hydrolase pth kmtR (requalified) — Ni(II)/Co(II)-sensing metalloregulatory transcript kmtR Rv1883c (family_assigned) — SRPBCC family protein Rv1883c rpfC (requalified) — resuscitation-promoting factor RpfC rpfC Rv3668c (requalified) — protease Rv3668c TB22.2 (family_assigned) — RsiV family protein TB22.2 cobIJ (requalified) — precorrin-2 C(20)-methyltransferase cobIJ Rv3166c (family_assigned) — DUF4129 domain-containing protein Rv3166c Rv2079 (family_assigned) — alpha/beta hydrolase Rv2079 eccB2 (family_assigned) — type VII secretion system ESX-2 subunit EccB2 eccB2 eccC2 (family_assigned) — type VII secretion system ESX-2 FtsK/SpoIIIE famil eccC2 Rv3900c (family_assigned) — hypothetical protein Rv3900c PE_PGRS16 (family_assigned) — PE-PGRS family protein PE_PGRS16 PE_PGRS16 blaC (requalified) — beta-lactamase blaC mycP2 (requalified) — type VII secretion system ESX-2 serine protease my mycP2 Rv3888c (family_assigned) — MinD/ParA family protein Rv3888c eccA2 (family_assigned) — type VII secretion system ESX-2 AAA family ATPase eccA2 eccE2 (family_assigned) — type VII secretion system ESX-2 subunit EccE2 eccE2 sdhC (family_assigned) — succinate dehydrogenase%2C cytochrome b556 subunit sdhC Rv0760c (family_assigned) — ketosteroid isomerase family protein Rv0760c kstD (requalified) — 3-oxosteroid 1-dehydrogenase kstD Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c Rv0247c (family_assigned) — succinate dehydrogenase/fumarate reductase iron-su Rv0247c frdB (family_assigned) — succinate dehydrogenase iron-sulfur subunit frdB sigL (family_assigned) — sigma-70 family RNA polymerase sigma factor SigL sigL Rv1145 (requalified) — transmembrane transport protein Rv1145 Rv0737 (family_assigned) — MarR family transcriptional regulator Rv0737 Rv1138c (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv1138c pks10 (requalified) — type III polyketide synthase pks10 Rv1146 (requalified) — transmembrane transport protein Rv1146 Rv3434c (family_assigned) — rhomboid-like protein Rv3434c Rv3433c (requalified) — NAD(P)H-hydrate dehydratase Rv3433c Rv3843c (family_assigned) — DUF4328 domain-containing protein Rv3843c Rv1006 (family_assigned) — hypothetical protein Rv1006 Rv1868 (family_assigned) — NAD(P)H-binding protein Rv1868

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.